We first describe the history and methods of membrane protein crystallization, and show how the structure of the photosynthetic reaction centre from the purple bacterium Rhodopseudomonas viridis was solved. The structure of this membrane protein complex is correlated with its function as a light-driven electron pump across the photosynthetic membrane. Finally we draw conclusions on the structure of the photosystem II reaction centre from plants and discuss the aspects of membrane protein structure.
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References
J. P. Allen G. Feher (1984) Proc. Natl. Acad. Sci. USA 81 4795–4799 Occurrence Handle6087348
J. P. Allen G. Feher T. O. Yeates D. C. Rees J. Deisenhofer H. Michel R. Huber (1986) Proc. Natl. Acad. Sci. USA 83 8589–8593 Occurrence Handle3022298
J. Alt J. Morris I. Westhoff R. G. Hermann (1984) Curr. Genet 8 597–606 Occurrence Handle10.1007/BF00395705
W. Baumeister W. Vogell (Eds) (1980) Electron Microscopy at Molecular Dimensions Springer Berlin
P. J. Bjorkmann M. A. Saper B. Samraoui W. S. Bennett J. Strominger D. C. Wiley (1987) Nature 329 506–512 Occurrence Handle10.1038/329506a0 Occurrence Handle3309677
J. Breton J. L. Martin A. Migus A. Antonetti A. Orszag (1986) Proc. Natl. Acad. Sci. USA 83 5121–5125
C. H. Chang M. Schiffer D. Tiede U. Smith J. Norris (1985) J. Mol. Biol 186 201–203 Occurrence Handle10.1016/0022-2836(85)90270-0 Occurrence Handle3908691
C. H. Chang D. Tiede J. Tang U. Smith J. Norris M. Schiffer (1986) FEBS Lett 205 82–86 Occurrence Handle10.1016/0014-5793(86)80870-5 Occurrence Handle3527749
R. K. Clayton B. J. Clayton (1978) Biochim. Biophys. Acta 501 478–487 Occurrence Handle629961
R. J. Debus G. Feher M. Y. Okamura (1986) Biochemistry 25 2276–2287 Occurrence Handle10.1021/bi00356a064 Occurrence Handle3011083
R. J. Debus B. A. Barry G. T. Babcock L. McIntosh (1988) Proc. Natl. Acad. Sci. USA 85 427–430 Occurrence Handle2829186
J. Deisenhofer O. Epp K. Miki R. Huber H. Michel (1984) J. Mol. Biol 180 385–398 Occurrence Handle10.1016/S0022-2836(84)80011-X Occurrence Handle6392571
J. Deisenhofer O. Epp K. Miki R. Huber H. Michel (1985a) Nature 318 618–624 Occurrence Handle10.1038/318618a0
J. Deisenhofer S. J. Remington W. Steigemann (1985b) Meth. Enzymol 115 303–323
J. Deisenhofer H. Michel (1988) NoChapterTitle J. Breton A. Vermeglio (Eds) The Photosynthetic Bacterial Reaction Center Structure and Dynamics Plenum Press New York 1–3
S. M. Dracheava L. A. Drachev A. A. Konstantinov A. Y. Semenov V. P. Skulachev A. M. Arutjunjan V. A. Shuvalov S. M. Zaberezhnaya (1988) Eur. J. Biochem 171 253–264 Occurrence Handle10.1111/j.1432-1033.1988.tb13784.x Occurrence Handle2828052
G. Feher M. Y. Okamura (1978) NoChapterTitle R. K. Clayton W. R. Sistrom (Eds) The Photosynthetic Bacteria Plenum Press New York, London 349–386
G. R. Fleming J. L. Martin J. Breton (1988) Nature 333 190–192 Occurrence Handle10.1038/333190a0
R. M. Garavito J. P. Rosenbusch (1980) J. Cell Biol 86 327–329 Occurrence Handle10.1083/jcb.86.1.327 Occurrence Handle6252213
R. M. Garavito Z. Markovic-Housley J. A. Jenkins (1986) J. Crystal Growth 76 701–709 Occurrence Handle10.1016/0022-0248(86)90187-9
P. Gast T. J. Michalski J. E. Hunt J. R. Norris (1985) FEBS Lett 179 325–328 Occurrence Handle10.1016/0014-5793(85)80544-5
R. Henderson P. N. T. Unwin (1975) Nature 257 28–32
C. W. Hoganson G. T. Babcock (1988) Biochemistry 27 5848–5855 Occurrence Handle10.1021/bi00416a005
M. Hoppe P. Overath (1976) Biochem. Biophys. Res. Commun 72 1504–1511 Occurrence Handle10.1016/S0006-291X(76)80184-2 Occurrence Handle11792
K. Holschuh W. Bottomley P. R. Whitfield (1984) Nucleic Acid Res 12 8819–8834
R. Huber M. Schneider O. Epp I. Mayr A. Messerschmidt J. Pflugrath H. Kayser (1987) J. Mol. Biol 195 423–434 Occurrence Handle10.1016/0022-2836(87)90661-9 Occurrence Handle3656419
A. Jack M. Levitt (1978) Acta Crystallogr A34 931–935
Jones T. A., Bartels K., and Schwager P. (1977) In: The Rotation Method in Crystallography (Arndt U. W.,and Wonacott A. J., eds.) North Holland, Amsterdam, pp 105–117.
T. A. Jones (1978) J. Appl. Crystallogr 11 268–272 Occurrence Handle10.1107/S0021889878013308
C. Kirmaier D. Holten W. W. Parson (1985a) Biochim. Biophys. Acta 810 33–48
C. Kirmaier D. Holten W. W. Parson (1985b) Biochim. Biophys. Acta 810 49–61
C. Kirmaier D. Holten R. J. Debus G. Feher M. Y. Okamura (1986) Proc. Natl. Acad. Sci. USA 83 6407–6411
C. Kirmaier D. Holten (1987) Photosynth. Res 13 225–260 Occurrence Handle10.1007/BF00029401
E. W. Knapp S. F. Fischer W. Zinth M. Sander W. Kaiser J. Deisenhofer H. Michel (1985) Proc. Natl. Acad. Sci. USA 82 8463–8467
B. Lee F. M. Richard (1971) J. Mol. Biol 55 379–400 Occurrence Handle10.1016/0022-2836(71)90324-X Occurrence Handle5551392
P. V. Luzzati (1952) Acta Crystallogr 5 802–810 Occurrence Handle10.1107/S0365110X52002161
F. S. Matthews P. Argos M. Levine (1972) Cold Spring Harbor Symp. Quant. Biol 36 387–397 Occurrence Handle4508153
H. Michel (1982a) EMBO J 1 1267–1271
H. Michel (1982b) J. Mol. Biol 158 567–572 Occurrence Handle10.1016/0022-2836(82)90216-9
H. Michel (1983) Trends Biochem. Sci 8 56–59 Occurrence Handle10.1016/0968-0004(83)90390-0
H. Michel D. Osterhelt R. Henderson (1980) Proc. Natl. Acad. Sci. USA 77 338–342 Occurrence Handle6928627
H. Michel D. Oesterhelt (1980) Proc. Natl. Acad. Sci. USA 77 1283–1285 Occurrence Handle6929485
H. Michel J. Deisenhofer K. Miki K. A. Weyer F. Lottspeich (1983) NoChapterTitle E. Quagliariello F. Palmieri (Eds) Structure and Function of Membrane Proteins Elsevier Amsterdam 191–197
H. Michel K. A. Weyer H. Gruenberg F. Lottspeich (1985) EMBO J 4 1667–1672
H. Michel K. A. Weyer H. Gruenberg I. Dunger D. Oesterheit F. Lottspeich (1986a) EMBO J 5 1144–1158
H. Michel O. Epp J. Deisenhofer (1986b) EMBO J 5 2445–2451
H. Michel J. Deisenhofer (1987) Chem. Scripta 27B 173–180
H. Michel J. Deisenhofer (1988) Biochemistry 27 1–7 Occurrence Handle10.1021/bi00401a001
M. E. Michel-Beyerle M. Plato J. Deisenhofer H. Michel M. Bixon J. Jortner (1988) Biochim. Biophys. Acta 932 52–70
H. Y. Nakatani B. Ke E. Dolan C. J. Arntzen (1984) Biochim. Biophys. Acta 765 347–352
O. Nanba K. Satoh (1987) Proc. Natl. Acad. Sci. USA 84 109–112
M. E. Newcomer T. A. Jones J. Aqvist J. Sundelin U. Eriksson I. Rask P. A. Peterson (1984) EMBO J 3 1451–1454 Occurrence Handle6540172
J. R. Norris R. A. Uphaus H. L. Crespi J. J. Katz (1971) Proc. Natl. Acad. Sci. USA 68 625–628 Occurrence Handle4993385
M. Y. Okamura G. Feher W. Nelson (1982) NoChapterTitle Govindjee (Eds) Photosynthesis: Energy Conversion by Plants and Bacteria NumberInSeriesVol. 1 Academic Press New York 195–272
T. Omata M. Murata K. Satoh (1984) Biochim. Biophys. Acta 765 403–405
Parson W. W. (1987) In: New Comprehensive Biochemistry: Photosynthesis (Amesz J., ed.) Elsevier, pp 43–61
W. W. Parson B. Ke (1982) NoChapterTitle Govindjee (Eds) Photosynthesis: Energy Conversion by Plants and Bacteria NumberInSeriesVol. 1 Academic Press New York 331–384
K. Pfister K. E. Steinback G. Gardner C. J. Arntzen (1981) Proc. Natl. Acad. Sci USA 78 981–985
A. P. Pugsley C. Chapon M. Schwartz (1986) J. Biol. Chem 256 2194–2198
O. F. Rasmussen G. Bookjans B. M. Stummann K. W. Henningen (1984) Plant Mol. Biol 3 191–199
J. D. Rochaix M. Dron M. Rahire P. Maloe (1984) Plant Mol. Biol 3 363–370 Occurrence Handle10.1007/BF00033383
M. G. Rossmann (1979) J. Appl. Crystallogr 12 225–238 Occurrence Handle10.1107/S0021889879012218
M. F. Schmid L. H. Weaver M. A. Holmes M. G. Gruetter D. H. Ohlendorf R. A. Reynolds S. J. Remington B. W. Matthews (1981) Acta Crystallogr A37 701–710
P. Schwager K. Bartels A. Jones (1975) J. Appl. Crystallogr 8 275–280 Occurrence Handle10.1107/S002188987501045X
V. H. Shuvalov U. V. Klimov (1976) Biochim. Biophys. Acta 440 587–599 Occurrence Handle183814
I. Sinning H. Michel (1987a) NoChapterTitle J. Biggins (Eds) Progress in Photosynthesis Research NumberInSeriesVol 3 Martinus Nijhoff Dordrecht III.11.771–III.11.773
I. Sinning H. Michel (1987b) Z. Naturforsch 42 751–754
D. M. Tiede R. C. Prince G. H. Reed P. L. Dutton (1976) FEBS Lett 65 301–304 Occurrence Handle10.1016/0014-5793(76)80134-2 Occurrence Handle182533
D. E. Tronrud L. F. Ten Eyck B. W. Matthews (1987) Acta Crystallogr A43 489–501
J. N. Varghese W. G. Laver P. M. Colman (1983) Nature 303 35–40 Occurrence Handle10.1038/303035a0 Occurrence Handle6843658
W. F. Vermaas A. W. Rutherford O. Hansson (1988) Proc. Natl. Acad. Sci. USA 85 8477–8481
C. Vitry Particlede B. Diner (1984) FEBS Lett 167 327–331 Occurrence Handle10.1016/0014-5793(84)80151-9
B. C. Wang (1985) Meth. Enzymol 115 90–112 Occurrence Handle4079800
K. A. Weyer W. Schäfer F. Lottspeich H. Michel (1987a) Biochemistry 26 2909–2914 Occurrence Handle10.1021/bi00384a036
Weyer K. A., Schäfer W., Lottspeich F. and Michel H. (1987b) In: Cytochrome Systems, (Papa S., Chanee B. and Ernster L., eds.) Plenum Publishing Corporation, pp. 235–331
K. A. Weyer F. Lottspeich H. Gruenberg F. Lang D. Oesterhelt H. Michel (1987b) EMBO J 6 2197–2202
J. C. Williams L. A. Steiner R. C. Ogden M. I. Simon G. Feher (1983) Proc. Natl. Acad. Sci. USA 80 6505–6509
J. C. Williams L. A. Steiner G. Feher M. I. Simon (1984) Proc. Natl. Acad. Sci. USA 81 7303–7307 Occurrence Handle6095283
J. C. Williams L. A. Steiner G. Feher (1986) Proteins Structure Function and Genetics 1 312–325 Occurrence Handle10.1002/prot.340010405
I. A. Wilson J. J. Skehel D. C. Wiley (1981) Nature 289 366–373 Occurrence Handle10.1038/289366a0 Occurrence Handle7464906
D. C. Youvan E. J. Bylina M. Alberti H. Requsch J. E. Heuvet (1984) Cell 37 949–957 Occurrence Handle10.1016/0092-8674(84)90429-X Occurrence Handle6744416
F. Yu S. Inouye M. Inouye (1986) J. Biol. Chem 261 2284–2288 Occurrence Handle3003106
W. Zinth W. Kaiser H. Michel (1983) Biochim. Biophys. Acta 723 128–131
W. Zinth E. W. Knapp S. F. Fischer W. Kaiser J. Deisenhofer H. Michel (1985) Chem. Phys. Lett 119 1–4 Occurrence Handle10.1016/0009-2614(85)85409-9
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Published in Les Prix Nobel–The Nobel Prizes 1988 (Nobel Foundation, Stockholm, 1989) and republished here with the permission of the Nobel Foundation the copyright holders.
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Deisenhofer, J., Michel, H. The Photosynthetic Reaction Centre from the Purple Bacterium Rhodopseudomonas viridis. Biosci Rep 24, 323–361 (2004). https://doi.org/10.1007/s10540-005-2737-4
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DOI: https://doi.org/10.1007/s10540-005-2737-4