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Synthesis, characterization and antimicrobial properties of a Co(II)-phthalylsulfathiazolate complex

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Abstract

The reaction between phthalylsulfathiazole (H2PST), in alkaline aqueous solution, and cobalt(II) nitrate led to a pink solid, [Co(PST)(H2O)4] (1), which was characterized by elemental and thermogravimetric analysis; FT-IR, Raman and diffuse reflectance spectra. Spectroscopic data reveal that the ligand would be doubly deprotonated and that the Co(II) ion environment is a distorted octahedral one. (1) showed antibacterial activity similar to the ligand.

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Acknowledgments

P.A.M.W. is member of the Research Career CICPBA. M.R. is member of the Research Career of UNR. M.R. acknowledges Prof. S. Zacchino for helpful discussions, Prof. A. M. Atria for elemental analysis and Rosario National University for financial support. AP thanks National Research Council of Argentina (CONICET) for a PhD scholarship and Fundación Prats for financial support.

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Authors and Affiliations

  1. Química Inorgánica, Universidad Nacional de Rosario, Suipacha 531, 2000, Rosario, Argentina

    Laura Monti, Ana Pontoriero, Natalia Mosconi, Cecilia Giulidori, Estela Hure & Marcela Rizzotto

  2. Facultad de Ciencias Exactas, CEQUINOR, UNLP, cc. 962, La Plata, Argentina

    Patricia A. M. Williams

  3. Farmacognosia, Universidad Nacional de Rosario, Suipacha 531, 2000, Rosario, Argentina

    María Victoria Rodríguez

  4. Facultad de Ingeniería, Instituto de Biotecnología, Universidad Nacional de San Juan, Avda. Libertador Gral, 1109-oeste-CP 5400, San Juan, San Martín, Argentina

    Gabriela Feresin

  5. Facultad de Ingeniería Química, UNL, Santiago del Estero 2829, 3000, Santa Fe, Argentina

    Darío Campagnoli

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  1. Laura Monti
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  2. Ana Pontoriero
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Monti, L., Pontoriero, A., Mosconi, N. et al. Synthesis, characterization and antimicrobial properties of a Co(II)-phthalylsulfathiazolate complex. Biometals 23, 1015–1028 (2010). https://doi.org/10.1007/s10534-010-9347-8

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