Abstract
Erythromycin production by Saccharopolyspora erythraea immobilized in 2% (w/v) calcium alginate or grown in medium containing 20 g sodium alginate/l inoculated with free cells was almost twice more than that of the control. S. erythraea did not consume alginate, agar, dextran, silicon antifoaming agent or cyclodextrin as a carbon source, although, all of these increased the production of erythromycin. Highest titer of erythromycin (2.3 times more than that of the control) was achieved in medium containing 1 g agar/l.
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Hamedi, J., Khodagholi, F. & Hassani-Nasab, A. Increased erythromycin production by alginate as a medium ingredient or immobilization support in cultures of Saccharopolyspora erythraea. Biotechnol Lett 27, 661–664 (2005). https://doi.org/10.1007/s10529-005-4476-9
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DOI: https://doi.org/10.1007/s10529-005-4476-9