Summary
Mycelia of Streptomyces erythreus were immobilized in calcium alginate beads and employed for production of erythromycin. Compared to conventional and washed mycelial fermentation, the average specific productivity of immobilised mycelia was superior.
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Bucke, C. (1987). Cell immobilisation in calcium alginate. In: Methods in Enzymology, Klaus Mosbach eds., Vol. 135, Part B, pp. 175–189, London: Academic press.
Code of Federal Regulations (1981). Title 21 - Food and Drugs, pp. 247–260. U.S. Govt. of Printing Office, Washington D.C.
Deo, Y.M. and Gaucher, G.M. (1984). Biotechnol. Bioeng. 26, 285–295.
Escalante, L., Lopez, H., Del Carmen, M.R., Lora, F. and Sanchez, S. (1982). J. Gen. Microbiol. 128(9), 2011–2015.
Flanagan, W.P., Klei, H.E., Sandstrom, D.W. and Lawton, C.W. (1990). Biotechnol. Bioeng. 36(6), 608–616.
Lowry, O.H., Rosebrough, N.J., Farr, A.L. and Randall, R.J. (1951). J. Biol. Chem. 193, 265–275.
Mandal, S.K., Bandyopadhyay, A. and Das, A.K. (1988). Ind. J. Exp. Biol. 26, 25–27.
Morikawa, Y., Karube, I. and Suzuki, S. (1980). Biotechnol. Bioeng. 22, 1015–1023.
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Bandyopadhyay, A., Das, A.K. & Mandal, S.K. Erythromycin production by Streptomyces erythreus entrapped in calcium alginate beads. Biotechnol Lett 15, 1003–1006 (1993). https://doi.org/10.1007/BF00129926
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DOI: https://doi.org/10.1007/BF00129926