Transcription factor PRH/Hhex suppresses cell proliferation and contributes to regulation of prenatal and postnatal ontogeny. Neurons of the peripheral nervous system and chromaffin cells were previously considered as non-expressing PRH/Hhex in postnatal development. In our study, the expression of PRH/Hhex in chromaffin cells of rat adrenal glands and association between the decrease of proliferation and activation of PRH/Hhex expression were demonstrated.
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 165, No. 4, pp. 505-508, April, 2018
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Yaglova, N.V., Obernikhin, S.S., Tsomartova, D.A. et al. Expression of Transcription Factor PRH/Hhex in Adrenal Chromaffin Cells in the Postnatal Development and Its Role in the Regulation of Proliferative Processes. Bull Exp Biol Med 165, 508–511 (2018). https://doi.org/10.1007/s10517-018-4205-8
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DOI: https://doi.org/10.1007/s10517-018-4205-8