We performed screening of potential antioxidants among natural lactone and alkaloid derivatives and characterized their antioxidant effects. The substances exhibiting antioxidant and metal-chelating potential, in particular, tryptamine derivatives, are promising neuroprotector agents.
Similar content being viewed by others
References
V. G. Artyukhov and M. A. Nakvasina, Biological Membranes: Structural Organization, Functions, and Modification with Physicochemical Agents [in Russian], Voronezh (2000).
R. M. C. Dawson, D. C. Elliott, W. H. Elliott, et al., Data for Biochemical Research [Russian translation], Moscow (1991).
W. Brand-Williams, M. E. Cuvelier, and C. Berset, Lebensm.-Wiss. u.-Technol., 28, 25–30 (1995).
С. А. Perez, Y. Wei, and M. Guo, J. Inorg. Biochem., 103, No. 3, 326–332 (2009).
I. Gulcin and V. Mshvidadze, Gepdiremen Phytomedicine, 13, 343–351 (2006).
Manfred Hesse, Alkaloids. Nature’s Curse or Blessing. Wiley-VCH (2002).
Author information
Authors and Affiliations
Corresponding author
Additional information
Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 152, No. 12, pp. 660–663, December, 2011
Rights and permissions
About this article
Cite this article
Neganova, M.E., Afanas’eva, S.V., Klochkov, S.G. et al. Mechanisms of antioxidant effect of natural sesquiterpene lactone and alkaloid derivatives. Bull Exp Biol Med 152, 720–722 (2012). https://doi.org/10.1007/s10517-012-1615-x
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10517-012-1615-x