The method of mid-infrared molecular spectroscopy allows precise measuring of the concentrations of a large number of biological molecules in a minimal sample volume. Method of projections on latent structures was used for plotting the calibration models. On the basis on mid-infrared spectral data we obtained calibration models for calculation of serum content of various substances: albumin, cholesterol, glucose, total protein, urea, 70 Da heat shock protein, and malonic dialdehyde.
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References
D. A. Sakharov, M. U. Shkurnikov, A. V. Stepanov, and A. G. Tonevitsky, Bull. Exper. Biol., 147, No. 3, 335-340 (2009).
K. Ebensen. Analysis of Multidimetional Data [in Russian]. Мoscow (2005).
L. Benezzeddine-Boussaidi, G. Cazorla, and A. M. Melin, Clin. Chem. Lab. Med., 47, No. 1, 83-90 (2009).
J. T. Borden, A. Man, D. A. Scott, and K.-Z. Liu, J. Mol. Med., 81, No. 12, 788-794 (2003).
C. E. Christersson, L. Lindh, and T. Arnebrant, Eur. J. Oral. Sci., 108, No 5, 418-425 (2000).
V. R. Kondepati, H. M. Heise, T. Oszinda, et al., Vibrat. Spectrosc., 46, 150-157 (2009).
X.-Y. Li and C. K. Chow, Lipids, 29, No. 1, 73-75 (1994).
C. Merle and A. Baillet-Guffroy, Biochim. Biophys. Acta., 1788, No. 5, 1092-1098 (2009).
H. Panayiotou and S. Kokot, Anal. Chim. Acta, 392, 223-235 (1999).
C. Petibois, G. Cazorla, A. Cassaigne, and G. Deleris, Clin. Chem., 47, No. 4, 730-738 (2001).
C. Petibois, G. Cazorla, and G. Deleris, Appl. Spectrosc., 56, No. 1, 10-16 (2002).
C. Petibois, K. Gionnet, M. Goncalves, et al., Analyst., 131, No. 5, 640-647 (2006).
O. Preisner, J. A. Lopes, R. Guiomar, et al., Anal. Bioanal. Chem., 387, No. 5, 1739-1748 (2007).
A. Sakudo, H. Kuratsune, Y. H. Kato, and K. Ikuta, Clin. Chim. Acta., 402, Nos. 1-2, 75-78 (2009).
Y. P. Zhou, L. Xu, L.-J. Tang, et al., Anal. Sci., 23, No. 7, 793-798 (2007).
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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 148, No. 12, pp. 707-711, December, 2009
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Khaustova, S.A., Davydov, I.I., Trushkin, E.V. et al. Application of Mid-Infrared Molecular Spectroscopy for Assessment of Biochemical Parameters of Blood Serum. Bull Exp Biol Med 148, 943–947 (2009). https://doi.org/10.1007/s10517-010-0858-7
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DOI: https://doi.org/10.1007/s10517-010-0858-7