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Reaction of Bcl-2-Positive Splenic Cells to Glucocorticoids

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Study of the glucocorticoid effects on the counts of Bcl-2-positive cells in various zones of the spleen showed that dexamethasone and prednisolone stimulated migration of apoptosis-resistant cells to the spleen, but their effects on cell distribution in various morphofunctional zones of the spleen were different. The population of Bcl-2-positive cells is divided into morphotypes, differing by location and reaction to glucocorticoids.

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Authors and Affiliations

  1. Laboratory of Medical Biology Department, Chuvash State University, Cheboksary, Russia

    E. M. Luzicova & O. A. Efimova

Authors
  1. E. M. Luzicova
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  2. O. A. Efimova
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Correspondence to E. M. Luzicova.

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Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 147, No. 2, pp. 220-224, February, 2009

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Luzicova, E.M., Efimova, O.A. Reaction of Bcl-2-Positive Splenic Cells to Glucocorticoids. Bull Exp Biol Med 147, 257–261 (2009). https://doi.org/10.1007/s10517-009-0470-x

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  • DOI: https://doi.org/10.1007/s10517-009-0470-x

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