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Revealing the Effect of Skull Deformation on Intracranial Pressure Variation During the Direct Interaction Between Blast Wave and Surrogate Head

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Abstract

Intracranial pressure (ICP) during the interaction between blast wave and the head is a crucial evaluation criterion for blast-induced traumatic brain injury (bTBI). ICP variation is mainly induced by the blast wave transmission and skull deformation. However, how the skull deformation influences the ICP remains unclear, which is meaningful for mitigating bTBI. In this study, both experimental and numerical models are developed to elucidate the effect of skull deformation on ICP variation. Firstly, we performed the shock tube experiment of the high-fidelity surrogate head to measure the ICP, the blast overpressure, and the skull surface strain of specific positions. The results show that the ICP profiles of all measured points show oscillations with positive and negative change, and the variation is consistent with the skull surface strain. Further numerical analysis reveals that when the blast wave reaches the measured point, the peak overpressure transmits directly through the skull to the brain, forming the local positive ICP peak, and the impulse induces the local inward deformation of the skull. As the peak overpressure passes through, the blast impulse impacts the nearby skull supported by the soft and incompressible brain tissue and extrudes the skull outward in the initial position. The inward and outward skull deformation leads to the oscillation of ICP. These numerical analyses agree with experimental results, which explain the appearance of negative and positive ICP peaks and the synchronization of negative ICP with surface strain. The study has implications for medical injury diagnosis and protective equipment design.

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Acknowledgments

This work is supported by the Science Challenge Project, No. TZ2018002, National Natural Science Foundation of China, under Grant Nos. 11972205, 11921002 and 11972210, the National Key Research Development Program of China (No. 2020-JCJQ-ZD-254).

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No benefits in any form have been or will be received from a commercial party related directly or indirectly to the subject of this manuscript.

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  1. School of Aerospace Engineering, Tsinghua University, Beijing, 100084, P.R. China

    Zhibo Du, Zhijie Li, Peng Wang, Xinghao Wang, Jiarui Zhang, Zhuo Zhuang & Zhanli Liu

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Du, Z., Li, Z., Wang, P. et al. Revealing the Effect of Skull Deformation on Intracranial Pressure Variation During the Direct Interaction Between Blast Wave and Surrogate Head. Ann Biomed Eng 50, 1038–1052 (2022). https://doi.org/10.1007/s10439-022-02982-5

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