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Estimation of Viscous Dissipative Stresses Induced by a Mechanical Heart Valve Using PIV Data

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Abstract

Among the clinical complications of mechanical heart valves (MHVs), hemolysis was previously thought to result from Reynolds stresses in turbulent flows. A more recent hypothesis suggests viscous dissipative stresses at spatial scales similar in size to red blood cells may be related to hemolysis in MHVs, but the resolution of current instrumentation is insufficient to measure the smallest eddy sizes. We studied the St. Jude Medical (SJM) 27 mm valve in the aortic position of a pulsatile circulatory mock loop under physiologic conditions with particle image velocimetry (PIV). Assuming a dynamic equilibrium assumption between the resolved and sub-grid-scale (SGS) energy flux, the SGS energy flux was calculated from the strain rate tensor computed from the resolved velocity fields and the SGS stress was determined by the Smagorinsky model, from which the turbulence dissipation rate and then the viscous dissipative stresses were estimated. Our results showed Reynolds stresses up to 80 N/m2 throughout the cardiac cycle, and viscous dissipative stresses below 12 N/m2. The viscous dissipative stresses remain far below the threshold of red blood cell hemolysis, but could potentially damage platelets, implying the need for further study in the phenomenon of MHV hemolytic complications.

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Acknowledgments

This work was supported by the National Science Council of the Republic of China Grant NSC 96-2221-E-032-048-MY3 and we thank the Division of Medical Engineering, National Health Research Institutes of the Republic of China for providing their technical assistance and primary laboratory equipment.

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Authors and Affiliations

  1. Water Resources and Environmental Engineering, Tamkang University, 151 Ying-Chuan Road, Tamsui, Taipei County, 251, Taiwan

    Chi-Pei Li & Po-Chien Lu

  2. Division of Medical Engineering, National Health Research Institutes, Miaoli, 350, Taiwan

    Chi-Wen Lo

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  1. Chi-Pei Li
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Correspondence to Po-Chien Lu.

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Associate Editor Julia E. Babensee oversaw the review of this article.

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Li, CP., Lo, CW. & Lu, PC. Estimation of Viscous Dissipative Stresses Induced by a Mechanical Heart Valve Using PIV Data. Ann Biomed Eng 38, 903–916 (2010). https://doi.org/10.1007/s10439-009-9867-y

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  • DOI: https://doi.org/10.1007/s10439-009-9867-y

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