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Phlorotannins as Radical Scavengers from the Extract of Sargassum ringgoldianum

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Abstract

To screen algal phlorotannins with antioxidative activities, 50% ethanol extracts of 25 Japanese marine algae were evaluated. Scavenging activity against superoxide anion radicals was frequently found with a high content of total phenolic compounds. Among these, the extract from the brown seaweed, Sargassum ringgoldianum, showed the strongest scavenging activity. The active fraction contained a mixture of high molecular weight polyphenols, phlorotannins that were found to be polymerized bifuhalol, as analyzed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS). The scavenging activity of the fraction against superoxide anion radicals was estimated to be 1.0 μg/ml (IC50), which were approximately five times stronger than that of catechin.

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Authors and Affiliations

  1. Suntory Research Center, Suntory, Ltd., Wakayamadai 1-1-1, Shimamoto-cho, Mishima-gun, Osaka, 618-8503, Japan

    Masaaki Nakai, Norihiko Kageyama, Koichi Nakahara & Wataru Miki

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  1. Masaaki Nakai
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  2. Norihiko Kageyama
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  3. Koichi Nakahara
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  4. Wataru Miki
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Correspondence to Masaaki Nakai.

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Nakai, M., Kageyama, N., Nakahara, K. et al. Phlorotannins as Radical Scavengers from the Extract of Sargassum ringgoldianum . Mar Biotechnol 8, 409–414 (2006). https://doi.org/10.1007/s10126-005-6168-9

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  • DOI: https://doi.org/10.1007/s10126-005-6168-9

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