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4-Amino and 5-aminobenzothiadiazoles in Gould–Jacobs reaction

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Abstract

4-Amino and 5-aminobenzothiadiazoles were prepared and submitted to reaction with activated enolethers to prepare N-substituted benzothiadiazolylaminoethylene derivatives. Selected aminoethylenes were thermally cyclized to angularly annelated thiadiazolylaminoethylene under Gould–Jacobs reaction conditions. Prepared products were modified to obtain variously substituted thiadiazoloquinolones.

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Acknowledgements

This work was supported by the Slovak Research and Development Agency under the contract no. APVV-17-0513.

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Authors and Affiliations

  1. Institute of Organic Chemistry, Catalysis and Petrochemistry, Slovak University of Technology, Radlinského Street 9, 812 37, Bratislava, Slovakia

    Viktor Milata & Martin Vaculka

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  1. Viktor Milata
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  2. Martin Vaculka
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Correspondence to Viktor Milata.

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Milata, V., Vaculka, M. 4-Amino and 5-aminobenzothiadiazoles in Gould–Jacobs reaction. Monatsh Chem 150, 711–719 (2019). https://doi.org/10.1007/s00706-019-2378-0

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  • DOI: https://doi.org/10.1007/s00706-019-2378-0

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