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Solid-phase microextraction coupled to gas chromatography with flame ionization detection for monitoring of organic solvents in working areas

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Abstract

A solid-phase microextraction (SPME) method was developed for air monitoring of organic solvents frequently used in chemical laboratories (namely pentane, dimethyl ether, acetone, acetonitrile, dichloromethane, hexane, ethylacetate, tetrahydrofurane, cyclohexane, benzene, and toluene). SPME sampling conditions and chromatographic separation were optimised. Linearity of response for each component of the mixture was tested. Standard solutions containing all the compounds, at three different concentrations, were analysed in triplicate and the relative standard deviations (RSDs) were calculated. The method was applied to the monitoring of indoor air in a research chemical laboratory. An SPME fibre was used as a sampling device inside the laboratory. Moreover an SPME fibre was used as a portable sampling device in order to determine the effective human exposure. Comparison of the portable and fixed sampling device showed differences in the amount of solvents associated with activities performed nearby.

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Authors and Affiliations

  1. Department of Chemistry “G. Ciamician”, University of Bologna, via F. Selmi 2, I-40126, Bologna, Italy

    Paola Bocchini, Romina Pozzi, Francesca Pinelli & Guido C. Galletti

  2. CNR-IMM, National Council of Research, Microelectronics and Microsystems Institute, University of Lecce, via per Arnesano A3 Building, I-73100, Lecce, Italy

    Danilo Dello Monaco

Authors
  1. Paola Bocchini
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  2. Danilo Dello Monaco
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  3. Romina Pozzi
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  4. Francesca Pinelli
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  5. Guido C. Galletti
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Correspondence to Paola Bocchini.

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Bocchini, P., Dello Monaco, D., Pozzi, R. et al. Solid-phase microextraction coupled to gas chromatography with flame ionization detection for monitoring of organic solvents in working areas. Microchim Acta 165, 271–278 (2009). https://doi.org/10.1007/s00604-008-0128-9

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  • DOI: https://doi.org/10.1007/s00604-008-0128-9

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