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Quality of life in patients with non-metastatic breast cancer: evolution during follow-up and vulnerability factors

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Abstract

Objective

In women with breast cancer, many disease-related psychosocial factors directly affect quality of life (QoL) during and after treatment. The aims of this prospective study were to evaluate the psychosocial factors affecting QoL and its dimensions, to study their evolution over time, and to determine the factors associated with this evolution.

Methods

Thirty women with non-metastatic breast cancer were asked to complete a number of questionnaires evaluating QoL and its dimensions, symptoms of anxiety and depression, body image, social support, and coping strategies immediately after their diagnosis of breast cancer (T1), at the end of treatment (T2), and 6 months after the end of treatment (T3).

Results

Level of education, mastectomy, and hormonotherapy all had an impact on QoL. QoL and its dimensions changed over time. Coping strategies, social support, body image, and symptoms of anxiety and depression were predictive factors for QoL.

Conclusion

The identification of these predictive factors should help medical teams to identify the patients who are most vulnerable and susceptible to poor QoL. In women with breast cancer, it is essential to identify and treat any changes in patients’ need for support in an appropriate manner, both during the course of therapy and particularly during remission.

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Availability of data and material

All the authors made sure that all dates and materials as well as software applications or custom codes support their published claims and comply with field standards.

Code availability

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Author information

Authors and Affiliations

  1. Hôpital Privé Drôme Ardèche, 07 500, Guilherand-Granges, France

    Sophie Lantheaume

  2. Laboratoire Inter-universitaire de Psychologie : Personnalité, Cognition et Changement Social (LIP PC2S), Université Grenoble Alpes, 38 400, Saint-Martin-d’Hères, France

    Sophie Lantheaume

  3. Aix Marseille Univ, PSYCLE, Aix en Provence, France

    Sophie Lantheaume, Lydia Fernandez & Ladislav Moták

  4. Laboratoire sur les Vulnérabilités et l’Innovation dans le Sport (EA 7428), Université Lumière Lyon 1, 69 622, Villeurbanne, France

    Lydia Fernandez

  5. Institut Du Sein Drôme Ardèche, 07 500, Guilherand-Granges, France

    Stéphane Lantheaume

  6. Université Lumière Lyon 2, DIPHE, 69 679, Bron, France

    Stéphanie Blois-Da Conceição

Authors
  1. Sophie Lantheaume
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  2. Lydia Fernandez
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  3. Stéphane Lantheaume
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  4. Ladislav Moták
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  5. Stéphanie Blois-Da Conceição
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Contributions

All the authors contributed to the study’s conception and design. Material preparation and data collection were performed by Sophie Lantheaume. Data analysis was performed by Ladislav Moták. The first draft of the manuscript was written by Sophie Lantheaume, and all the authors commented on previous versions of the manuscript. All the authors read and approved the final manuscript.

Corresponding author

Correspondence to Sophie Lantheaume.

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The authors declare no competing interests.

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Lantheaume, S., Fernandez, L., Lantheaume, S. et al. Quality of life in patients with non-metastatic breast cancer: evolution during follow-up and vulnerability factors. Support Care Cancer 30, 1935–1943 (2022). https://doi.org/10.1007/s00520-021-06203-y

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  • DOI: https://doi.org/10.1007/s00520-021-06203-y

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