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Evolution of the structure and composition of house mouse satellite DNA sequences in the subgenus Mus (Rodentia: Muridea): a cytogenomic approach

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Abstract

The composition and orientation of the house mouse satellite DNA sequences (minor, major, TLC) were investigated by a FISH and CO-FISH approach in 11 taxa belonging to three clades of the subgenus Mus. Using a phylogenetic framework, our results highlighted two distribution patterns. The TLC satellite, the most recently discovered satellite, was present in all clades but varied quantitatively among species. This distribution supported its appearance in the ancestor of the subgenus followed by independent evolution in species of each clade. In contrast, the minor and major satellites occurred in only two clades of the subgenus indicating the simultaneous and recent amplification of these sequences. In addition, although qualitative differences in the composition and orientation of the satellite sequences were observed among the taxa, none of the features studied were unique to the house mouse and could account for the extensive chromosomal plasticity evidenced in Mus musculus domesticus.

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Acknowledgments

We are grateful to A. Orth for animal samples, C. Desmaze for her technical assistance in CO-FISH and P. Kalitsis for providing the major, minor and TLC probes. The Southern blot complement could not have been performed without the enlightened and much appreciated assistance of C. Mari, P. Caminade, E. Douzery, B. de Massy, J.-C. Davidian and C. Benoist. We are grateful to Gunilla Rosenqvist for assistance in the completion of this work. The GDR 3047 (Cytogénomique Structurale et Evolutive) financed a travel grant for training in CO-FISH procedures. All cytogenetic analyses were performed in the Plateforme de Cytogénomique Evolutive of the SFR MEB in Montpellier. This study was supported by recurrent funding from the CNRS and UM2.This is publication ISEM no. 2013-008.

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  1. B. Cazaux

    Present address: Centre for Conservation Biology, Department of Biology, Norwegian University of Science and Technology, NO-7491, Trondheim, Norway

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  1. Institut des Sciences de l’Evolution, Université Montpellier 2, cc065, Pl. E. Bataillon, 34095, Montpellier Cedex 05, France

    B. Cazaux, J. Catalan, F. Justy, E. Desmarais & J. Britton-Davidian

  2. Département Régulations, Développement & Diversité Moléculaire, Muséum National d’Histoire Naturelle, UMR7196 MNHN-CNRS, U565 INSERM, 43 rue Cuvier Case postale 26, 75231, Paris Cedex 05, France

    C. Escudé

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Cazaux, B., Catalan, J., Justy, F. et al. Evolution of the structure and composition of house mouse satellite DNA sequences in the subgenus Mus (Rodentia: Muridea): a cytogenomic approach. Chromosoma 122, 209–220 (2013). https://doi.org/10.1007/s00412-013-0402-4

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