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Urodynamic insights: exploring the relationship between detrusor overactivity and pelvic organ prolapse in women with urge incontinence

  • Urogynecology
  • Published:
Archives of Gynecology and Obstetrics Aims and scope Submit manuscript

Abstract

Purpose

Pelvic organ prolapse (POP) and overactive bladder (OAB) commonly affect the aging female population. We aimed to investigate the possible relationship between the two, as reflected by urodynamic studies.

Methods

A retrospective analysis was conducted on women who underwent urodynamic studies at a university-affiliated tertiary medical center from January 2018 to January 2021. Women presenting with urge incontinence and diagnosed with detrusor overactivity (DO) were included in the study. Based on the presence or absence of a modified POP-Q ≥ grade 2, these women were categorized into two groups. Data on general demographics, clinical symptoms, and urodynamic findings were extracted and compared using SPSS.

Results

During the study period, 949 urodynamic evaluations were performed. Of these, 303 (31.92%) reported urge incontinence. Out of this subset, 151 (49.83%) were diagnosed with DO. Within this group, 18 (11.9%) had POP, while 134 (88.1%) did not. The POP group had a notably higher incidence of prior vaginal hysterectomy and anterior colporrhaphy (p = 0.02 and p = 0.01, respectively). While most urodynamic parameters were similar between groups, there was a significant increase in hesitancy in the POP group (13 s vs 8 s, p = 0.03). There was a trend indicating a reduced median Q max (12 ml/s vs. 18 ml/s, p = 0.06) and an increased flow time (55 s vs 40 s, p = 0.08) in the POP group.

Conclusion

The urodynamic profile of the POP group suggests an obstructive voiding pattern. Further longitudinal research is essential to fully understand the relationship between POP and OAB.

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Data availability

The data that support the findings of this study are available on request from the corresponding author (RR).

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Acknowledgements

None.

Funding

No financial support was received for this study.

Author information

Author notes

  1. Reut Rotem and Simon Craven have equally contributed.

Authors and Affiliations

  1. Department of Urogynaecology, Cork University Maternity Hospital, Wilton Rd, Wilton, Cork, Ireland

    Reut Rotem, Simon Craven, Jessica Murphy, Daniel Galvin & Barry A. O’Reilly

  2. Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Affiliated with the Hebrew University School of Medicine, Jerusalem, Israel

    Reut Rotem

  3. Department of OBGYN, Meir Medical Center, Kfar Saba, Israel

    Yair Daykan

  4. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel

    Yair Daykan

Authors
  1. Reut Rotem
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  2. Simon Craven
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  3. Yair Daykan
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  4. Jessica Murphy
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  5. Daniel Galvin
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  6. Barry A. O’Reilly
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Contributions

RR: Protocol development, data collection and management, data analysis, manuscript writing/editing. SC: Protocol development, data collection and management, data analysis, manuscript writing/editing. YD: Data collection and management, manuscript writing/editing. JM: Data collection and management, manuscript writing/editing. DG: Data collection and management, manuscript writing/editing. BAO: Protocol development, data collection and management, data analysis, manuscript writing/editing.

Corresponding author

Correspondence to Reut Rotem.

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The authors report no conflict of interest.

Ethical approval

This study was performed in line with the principles of the Declaration of Helsinki. Approval was granted by the Ethics Committee of CUMH.

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Rotem, R., Craven, S., Daykan, Y. et al. Urodynamic insights: exploring the relationship between detrusor overactivity and pelvic organ prolapse in women with urge incontinence. Arch Gynecol Obstet (2024). https://doi.org/10.1007/s00404-024-07414-4

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  • DOI: https://doi.org/10.1007/s00404-024-07414-4

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