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The association between the levels of anti-Müllerian hormone (AMH) and dietary intake in Iranian women

  • General Gynecology
  • Published:
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Abstract

Purpose

This paper aimed to assess the association between AMH with dietary intake of adult women referred to the infertility clinic of Al-Zahra Hospital in Rasht, Iran.

Methods

This cross-sectional study was performed on 234 adult women referred to the infertility clinic of Al-Zahra Hospital, Rasht, Iran. The participants were categorized into two groups based on their AMH levels. Participants' data on lifestyle and anthropometry as well as blood samples were collected. Dietary intakes were assessed by a validated food frequency questionnaire (FFQ).

Results

Serum AMH concentration was negatively associated with the intake of fast foods (P = 0.002) and saturated fats (P = 0.040). These associations remained significant after adjustments for age, rural or urban location, and education. Additional adjustments for body mass index (BMI) and physical activity did not change the results. The results remained significant after further adjustments for menstrual age, menstrual pattern, and oral contraceptive pills.

Conclusion

Fast foods and saturated fats were significantly associated with lower AMH concentrations and modifying the amount of these dietary components may be an important strategy for increasing the reservation of ovaries in women. Future longitudinal studies are warranted to confirm these findings and to identify the underlying mechanisms.

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Data availability

All data supporting the results of our article will be made available from the corresponding author on reasonable request without undue reservations.

Abbreviations

AMH:

Anti-Müllerian hormone

PCOS:

Polycystic ovary syndrome

OR:

Ovarian reserve

OHSS:

Ovarian hyper-stimulation syndrome

FF:

Follicular fluid

BMI:

Body mass index

DASH:

Dietary approaches to stop hypertension

ml:

Millimeters

RPM:

Revolutions per minute

°C:

Degrees Celsius

ELISA:

Enzyme-linked immunosorbent assay

kg/m2 :

Kilogram per meter square

OCPs:

Oral contraceptive pills

IPAQ:

International physical activity questionnaire

FFQ:

Food frequency questionnaire

SD:

Standard deviation

F:

Frequency

P:

Probability

MUFAs:

Mono-unsaturated fatty acids

PUFAs:

Poly-unsaturated fatty acids

FO:

Fish oil

WGO:

Wheat-germ oil

ANCOVA:

Analysis of covariance

USDA:

United States Department of Agriculture

DHA:

Docosahexaenoic acid

DPA:

Docosapentaenoic acid

EPA:

Eicosapentaenoic acid

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Acknowledgements

We appreciated all participated women and staff in the infertility clinic of Al-Zahra Hospital and also, the staff in the Ethics Committee of Guilan University of Medical Sciences in Rasht for their best cooperation.

Funding

This study was financially supported by the Vice-Chancellorship of Research and Technology, Guilan University of Medical Sciences, Rasht, Iran. None of the funding bodies were involved in the research, writing, and publishing of this article.

Author information

Authors and Affiliations

  1. Reproductive Health Research Center, Department of Obstetrics and Gynecology, School of Medicine, Al-Zahra Hospital, Guilan University of Medical Sciences, Rasht, Iran

    Roya KaboodMehri, Ziba Zahiri Sorouri, Seyedeh Hajar Sharami & Shima Yazdipaz

  2. School of Paramedicine, Guilan University of Medical Sciences, Langroud, Iran

    Seyedeh Elaheh Bagheri

  3. Research Center of Health and Environment, School of Health, Guilan University of Medical Sciences, Rasht, Iran

    Saeid Doaei

  4. Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran

    Saeid Doaei

Authors
  1. Roya KaboodMehri
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  2. Ziba Zahiri Sorouri
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  3. Seyedeh Hajar Sharami
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  4. Seyedeh Elaheh Bagheri
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  5. Shima Yazdipaz
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  6. Saeid Doaei
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Contributions

All authors contributed to the study conception and design. RKM, ZZS, SHS, and SY conducted research. SD was involved in the analysis of the data. SEB and SD wrote the paper and prepared the final draft of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to Seyedeh Hajar Sharami.

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Conflict of interest

No potential competing interests were declared by the authors.

Ethical approval

The study was approved by the Ethics Committee of Guilan University of Medical Sciences, Rasht, Iran (Ethical code: IR.GUMS.REC.1398.375). All stages of this research have been performed according to the Helsinki declaration.

Consent to participate

All procedures of the study were explained clearly to the participants who had the eligible inclusion criterion. Moreover, all participants voluntarily filled out the written informed consent form before they join the study and they were free to decide whether or not to attend or withdraw at any time and for any reason without changing the medical care.

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KaboodMehri, R., Sorouri, Z.Z., Sharami, S.H. et al. The association between the levels of anti-Müllerian hormone (AMH) and dietary intake in Iranian women. Arch Gynecol Obstet 304, 687–694 (2021). https://doi.org/10.1007/s00404-021-06098-4

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  • DOI: https://doi.org/10.1007/s00404-021-06098-4

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