Zusammenfassung
Diese Übersichtsarbeit befasst sich mit der klinischen Anwendung und technischen Aspekten bildgebender Verfahren, die alternativ oder komplementär zur Angiographie und Magnetresonanztomographie bei Patienten mit Takayasu-Arteriitis oder Riesenzellarteriitis genutzt werden. Für die Beurteilung peripherer Arterien ist die Duplexsonographie aufgrund der hohen Ortsauflösung besonders geeignet. Mit der Positronenemissionstomographie als Methode zur Ganzkörperuntersuchung ist das Ausmaß der entzündlichen Aktivität abgesehen von kraniellen Arterien am besten zu erfassen. Die Computertomographie ermöglicht angiographische Untersuchungen und die Beurteilung von Wandverdickungen großer Arterien und ist Methode der Wahl bei Notfalluntersuchungen von Aneurysmen und Dissektionen der Aorta. Ophthalmologische Methoden beinhalten neben angiographischem und sonographischen Techniken die Biomikroskopie einschließlich Funduskopie sowie die optische Kohärenztomographie.
Abstract
This article focuses on the clinical application and technical aspects of imaging methods which are used alternatively or additionally to angiography or magnetic resonance imaging in patients with Takayasu’s arteritis or giant cell arteritis. Providing a high spatial resolution, duplex ultrasound is particularly suitable for the evaluation of peripheral arteries. With the exception of cranial arteries, positron emission tomography as a whole body examination is the best imaging modality for the assessment of inflammatory activity. Computed tomography is used for angiographic examinations and enables evaluation of wall thickening in large arteries. It is the method of choice in the case of emergencies due to aortic aneurysm or dissection. In addition to angiographic and ultrasound techniques, ophthalmological methods comprise biomicroscopy, including funduscopy and optical coherence tomography.
Literatur
Schmidt WA, Backhaus M (2008) What the practising rheumatologist needs to know about the technical fundamentals of ultrasonography. Best Pract Res Clin Rheumatol 22:981–999
Schmidt WA, Both M, Reinhold-Keller E (2006) Bildgebende Verfahren in der Rheumatologie: Bildgebung bei Vaskulitiden. Z Rheumatol 65:652–661
Karassa FB, Matsagas MI, Schmidt WA, Ioannidis JP (2005) Meta-analysis: test performance of ultrasonography for giant-cell arteritis. Ann Intern Med 142:359–369
Schmidt WA, Gromnica-Ihle E (2005) What is the best approach to diagnosing large-vessel vasculitis? Best Pract Res Clin Rheumatol 19:223–242
Romera-Villegas A, Vila-Coll R, Poca-Dias V, Cairols-Castellote MA (2004) The role of color duplex sonography in the diagnosis of giant cell arteritis. J Ultrasound Med 23:1493–1498
Karahaliou M, Vaiopoulos G, Papaspyrou S et al (2006) Colour duplex sonography of temporal arteries before decision for biopsy: a prospective study in 55 patients with suspected giant cell arteritis. Arthritis Res Ther 8:R116
Schmidt WA, Seifert A, Gromnica-Ihle E et al (2008) Ultrasound of proximal upper extremity arteries to increase the diagnostic yield in large-vessel giant cell arteritis. Rheumatology 47:96–101
Schmidt WA, Kraft HE, Borkowski A, Gromnica-Ihle EJ (1999) Color duplex ultrasonography in large-vessel giant cell arteritis. Scand J Rheumatol 28:374–376
Schmidt WA, Nerenheim A, Seipelt E et al (2002) Diagnosis of early Takayasu arteritis with sonography. Rheumatology 41:496–502
Maeda H, Handa N, Matsumoto M et al (1991) Carotid lesions detected by B-mode ultrasonography in Takayasu’s arteritis: ‚‚macaroni sign’‘ as an indicator of the disease. Ultrasound Med Biol 17:695–701
Bezerra Lira-Filho E, Campos O, Lazaro Andrade J et al (2006) Thoracic aorta evaluation in patients with Takayasu’s arteritis by transesophageal echocardiography. J Am Soc Echocardiogr 19:829–834
García-Martínez A, Hernández-Rodríguez J, Arguis P et al (2008) Development of aortic aneurysm/dilatation during the followup of patients with giant cell arteritis: a cross-sectional screening of fifty-four prospectively followed patients. Arthritis Rheum 59:422–430
Blodgett T (2008) Best practices in PET/CT: consensus on performance of positron emission tomography-computed tomography. Semin Ultrasound CT MR 29:236–241
Polisson RP, Schoenberg OI, Fischman A et al (1995) Use of magnetic resonance imaging and positron emission tomography in the assessment of synovial volume and glucose metabolism in patients with rheumatoid arthritis. Arthritis Rheum 38:819–825
Shreve PD, Anzai Y, Wahl RL (1999) Pitfalls in oncologic diagnosis with FDG PET imaging: physiologic and benign variants. Radiographics 19:61–77
Huang B, Law MW, Khong PL (2009) Whole-body PET/CT scanning: estimation of radiation dose and cancer risk. Radiology 251:166–174
Wagner AD, Andresen J, Raum E et al (2005) Standardised work-up programme for fever of unknown origin and contribution of magnetic resonance imaging for the diagnosis of hidden systemic vasculitis. Ann Rheum Dis 64:105–110
Blockmans D, de Ceuninck L, Vanderschueren S et al (2006) Repetitive 18F-fluorodeoxyglucose positron emission tomography in giant cell arteritis: a prospective study of 35 patients. Arthritis Rheum 55:131–137
Moosig F, Czech N, Mehl C et al (2004) Correlation between 18-fluorodeoxyglucose accumulation in large vessels and serological markers of inflammation in polymyalgia rheumatica: a quantitative PET study. Ann Rheum Dis 63:870–873
Brodmann M, Lipp RW, Passath A et al (2004) The role of 2–18F-fluoro-2-deoxy-D-glucose positron emission tomography in the diagnosis of giant cell arteritis of the temporal arteries. Rheumatology 43:241–242
Both M, Ahmadi-Simab K, Reuter M et al (2008) MRI and FDG-PET in the assessment of inflammatory aortic arch syndrome in complicated courses of giant cell arteritis. Ann Rheum Dis 67:1030–1033
Blockmans D, Coudyzer W, Vanderschueren S et al (2008) Relationship between fluorodeoxyglucose uptake in the large vessels and late aortic diameter in giant cell arteritis. Rheumatology 47:1179–1184
Breynaert C, Cornelis T, Stroobants S et al (2008) Systemic lupus erythematosus complicated with aortitis. Lupus 17:72–74
Salvarani C, Pipitone N, Versari A et al (2005) Positron emission tomography (PET): evaluation of chronic periaortitis. Arthritis Rheum 53:298–303
Bleeker-Rovers CP, Bredie SJ, van der Meer JW et al (2003) F-18-fluorodeoxyglucose positron emission tomography in diagnosis and follow-up of patients with different types of vasculitis. Neth J Med 61:323–329
Belhocine T, Blockmans D, Hustinx R et al (2003) Imaging of large vessel vasculitis with (18)FDG PET: illusion or reality? A critical review of the literature data. Eur J Nucl Med Mol Imaging 30:1305–1313
Scheel AK, Meller J, Vosshenrich R et al (2004) Diagnosis and follow up of aortitis in the elderly. Ann Rheum Dis 63:1507–1510
Arnaud L, Haroche J, Malek Z et al (2009) Is (18)F-fluorodeoxyglucose positron emission tomography scanning a reliable way to assess disease activity in takayasu arteritis? Arthritis Rheum 60:1193–1200
Dos Anjos DA, Dos Anjos RF, de Paula WD, Sobrinho AB (2008) F-18 FDG PET/CT in giant cell arteritis with polymyalgia rheumatica. Clin Nucl Med 33:402–404
Galanski M, Prokop M (2007) Ganzkörper-Computertomographie. Spiral- und Multislice-CT, 2. Aufl. Thieme, Stuttgart
Laswed T, Rizzo E, Guntern D et al (2008) Assessment of occlusive arterial disease of abdominal aorta and lower extremities arteries: value of multidetector CT angiography using an adaptive acquisition method. Eur Radiol 18:263–272
Wintersperger B, Jakobs T, Herzog P et al (2005) Aorto-iliac multidetector-row CT angiography with low kV settings: improved vessel enhancement and simultaneous reduction of radiation dose. Eur Radiol 15:334–341
Heyer CM, Peters S, Lemburg S, Nicolas V (2007) Einschätzung der Strahlenbelastung radiologischer Thorax-Verfahren: Was ist Nichtradiologen bekannt? Fortschr Röntgenstr 179:261–267
Nagel HD, Blobel J, Brix G et al (2004) 5 Jahre Konzertierte Aktion Dosisreduktion CT – was wurde erreicht, was ist noch zu tun? Fortschr Röntgenstr 176:1683–1694
Tavora F, Jeudy J, Gocke C, Burke A (2005) Takayasu aortitis with acute dissection and hemopericardium. Cardiovasc Pathol 14(6):320–323
Yamada I, Nakagawa T, Himeno Y et al (1998) Takayasu arteritis: evaluation of the thoracic aorta with CT angiography. Radiology 209:103–109
Klingebiel R, Kentenich M, Bauknecht HC et al (2008) Comparative evaluation of 64-slice CT angiography and digital subtraction angiography in assessing the cervicocranial vasculature. Vasc Health Risk Manag 4(4):901–907
Nakamura M, Nagano M (2004) Impact of multislice CT on coronary ostial stenosis in Takayasu’s arteritis. Heart 90:136
Yoshida S, Akiba H, Tamakawa M et al (2001) The spectrum of findings in supra-aortic Takayasu’s arteritis as seen on spiral CT angiography and digital subtraction angiography. Cardiovasc Intervent Radiol 24:117–121
Kim SY, Park JH, Chung JW et al (2007) Follow-up CT evaluation of the mural changes in active Takayasu arteritis. Korean J Radiol 8:286–294
Yannuzzi LA, Rohrer KT, Tindel LJ et al (1986) Fluorescein angiography complication survey. Ophthalmology 93:611–617
Huang D, Swanson EA, Lin CP et al (1991) Optical coherence tomography. Science 254:1178–1181
Interessenkonflikt
Der korrespondierende Autor gibt an, dass kein Interessenkonflikt besteht.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Both, M., Nölle, B., von Forstner, C. et al. Bildgebende Techniken zur Diagnostik primärer Großgefäßvaskulitiden. Z. Rheumatol. 68, 819–833 (2009). https://doi.org/10.1007/s00393-009-0565-9
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00393-009-0565-9