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Management of vestibular schwannomas in young patients—comparison of clinical features and outcome with adult patients

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Abstract

Objects

Vestibular schwannomas (VS) in young patients are rare. They are regarded to have different biological characteristics. Our objective is to analyze a series of such patients, with respect to their clinical presentation, treatment, and outcome and to compare the results to a matched series of adult patients.

Materials and methods

Retrospective analysis of 20 patients under 21 years of age. All patients underwent surgery via the retrosigmoid approach. The analysis included: age, gender, tumor size, clinical, and neurological pre- and postoperative status including cochlear and facial nerve function, and complications. Statistical comparison of the young patient’s data with a series of 200 adult patients previously published by the authors.

Conclusions

The current study demonstrates that the outcome after surgical management in patients harboring VS does not show any significant difference between young and adult patients.

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References

  1. Abe K, Yamasaki T, Fukuyama H (1985) A case report of pediatric acoustic neuroma. Clin Otol Jpn 12:134–135

    Google Scholar 

  2. Allcutt DA, Hoffman HJ, Isla A, Becker LE, Humphreys RP (1991) Acoustic schwannomas in children. Neurosurgery 29:14–18

    Article  PubMed  CAS  Google Scholar 

  3. Anderson DE, Leonetti J, Wind JJ, Cribari D, Fahey K (2005) Resection of large vestibular schwannomas: facial nerve preservation in the context of surgical approach and patient-assessed outcome. J Neurosurg 102:643–649

    PubMed  Google Scholar 

  4. Bjorkesten GA (1957) Unilateral acoustic tumors in children. Acta Psychiatr Neurol Scand 32:1–5

    PubMed  CAS  Google Scholar 

  5. Bull JG, Lipson AC, Martin AJ (2006) Giant vestibular schwannoma in a 12-year-old girl. Pediatr Neurosurg 42:338–340

    Article  PubMed  Google Scholar 

  6. Chen TC, Maceri DR, Giannotta SL, Shih L, McComb JG (1992) Unilateral acoustic neuromas in childhood without evidence of neurofibromatosis: case report and review of the literature. Am J Otol 13:318–322

    PubMed  CAS  Google Scholar 

  7. Chung WY, Liu KD, Shiau CY, Wu HM, Wang LW, Guo WY, Ho DM, Pan DH (2005) Gamma knife surgery for vestibular schwannoma: 10-year experience of 195 cases. J Neurosurg 102(Suppl):87–96

    PubMed  Google Scholar 

  8. Craig WM, Dodge HW Jr, Ross PJ (1954) Acoustic neuromas in children: report of 2 cases. J Neurosurg 11:505–508

    PubMed  CAS  Google Scholar 

  9. Erikson L, Sorenson G, McGavran M (1965) A review of 140 acoustic neuromas. Laryngoscope 75:601–627

    Google Scholar 

  10. Evans DGR, Lye R, Neary W, Black G, Strachan T, Wallace A, Ramsden RT (1999) Probability of bilateral disease in people presenting with a unilateral vestibular schwannoma. J Neurol Neurosurg Psychiatry 66:764–767

    PubMed  CAS  Google Scholar 

  11. Fabiani A, Croveri G, Torta R (1975) Neurinoma of the posterior fossa in a 1-year-old child. Acta Neurol 30:218–222

    CAS  Google Scholar 

  12. Forer M, Fagan PA (1987) Acoustic tumor in a young adult: documented growth rate. Am J Otol 8:108–110

    PubMed  CAS  Google Scholar 

  13. Frank T, May M, Janetta PJ (1978) Acoustic neurinoma in a child: a case study. J Speech Hear Disord 43:506–512

    PubMed  CAS  Google Scholar 

  14. Gaini SM, Giovanelli M, Motti ED, Tomei G, Villani R (1976) Acoustic neurinomas in infancy. Report on four cases. Mod Probl Paediatr 18:90–93

    PubMed  CAS  Google Scholar 

  15. Harada K, Nishizaki T, Adachi N, Suzuki M, Ito H (2000) Pediatric acoustic schwannoma showing rapid regrowth with high proliferative activity. Child’s Nerv Syst 16:134–137

    Article  CAS  Google Scholar 

  16. Hernanz-Schulman M, Welch K, Strand R, Ordia JI (1986) Acoustic neuromas in children. AJNR Am J Neuroradiol 7:519–521

    PubMed  CAS  Google Scholar 

  17. Hodes PJ, Pendergrass EP, Young BR (1949) Eighth nerve tumors; their roentgen manifestations. Radiology 53:633–665

    PubMed  CAS  Google Scholar 

  18. House WF (1968) Acoustic neuroma. Case summaries. Arch Otolaryngol 88:586–591

    PubMed  CAS  Google Scholar 

  19. House JW, Brackmann DE (1985) Facial nerve grading system. Otolaryngol Head Neck Surg 93:146–147

    PubMed  CAS  Google Scholar 

  20. Ishikawa K, Yasui N, Monoh K, Tada H, Mineura K, Sasajima H, Togawa K (1997) Unilateral acoustic neuroma in childhood. Auris Nasus Larynx 24:99–104

    Article  PubMed  CAS  Google Scholar 

  21. Krause CJ, McCabe BF (1971) Acoustic neuroma in a 7-year-old girl. Report of a case. Arch Otolaryngol 94:359–363

    PubMed  CAS  Google Scholar 

  22. Kusunose M, Nishijima M, Oka N, Yamatani K, Takaku A (1990) Acoustic neurinoma in a child. No Shinkei Geka 18:301–306

    PubMed  CAS  Google Scholar 

  23. Laha RK, Huestis WS (1975) Unilateral acoustic neuroma and cerebellopontine angle lesions in children. Surg Neurol 4:371–374

    PubMed  CAS  Google Scholar 

  24. Lang DA, Neil-Dwyer G, Evans BT, Honeybul S (1998) Craniofacial access in children. Acta Neurochir 140:33–40

    Article  CAS  Google Scholar 

  25. Lunsford L, Niranjan A, Flickinger JC, Maitz A, Kondziolka D (2005) Radiosurgery of vestibular schwannomas: summary of experience in 829 cases. J Neurosurg 102(Suppl):195–199

    PubMed  Google Scholar 

  26. Mark VH, Sweet WH (1952) An unusual case of unilateral eighth nerve tumor. J Neurosurg 9:395–397

    PubMed  CAS  Google Scholar 

  27. Matthies C, Samii M (1997) Management of 1000 Vestibular schwannomas (Acoustic Neuromas): clinical presentation. Neurosurgery 40:1–10

    Article  PubMed  CAS  Google Scholar 

  28. Mattucci KF, Glass WM, Setzen M, Levin W (1987) Childhood acoustic neuroma. N Y State J Med 87:665–666

    PubMed  CAS  Google Scholar 

  29. Neary W, Newton VE, Laiode-Kemp SN, Ramsden RT, Griffith G, Evans DG, Harris R, Strachan T (1996) A clinical, genetic and audiological study of patients with unilateral vestibular schwannomas. I. Clinical features of neurofibromatosis in patients with unilateral vestibular schwannomas. J Laryngol Otol 110:634–640

    PubMed  CAS  Google Scholar 

  30. O-Uchi T, Tanaka Y, Sakasita T (1986) A case of acoustic tumor in a child. Clin Otol Jpn 13:366–367

    Google Scholar 

  31. Pothula VB, Lesser T, Mallucci C, May P, Foy P (2001) Vestibular schwannomas in children. Otol Neurotol 22:903–907

    Article  PubMed  CAS  Google Scholar 

  32. Propp JM, McCarthy BJ, Davis FG, Preston-Martin S (2006) Descriptive epidemiology of vestibular schwannomas. Neuro-oncology 8:1–11

    Article  PubMed  Google Scholar 

  33. Rushworth RG, Sorby WA, Smith SF (1984) Acoustic neuroma in a child treated with the aid of preoperative arterial embolization. Case report. J Neurosurg 61:396–398

    Article  PubMed  CAS  Google Scholar 

  34. Samii M, Matthies C (1997) Management of 1000 vestibular schwannomas (acoustic neuromas): hearing function in 1000 tumor resections. Neurosurgery 40:248–262

    Article  PubMed  CAS  Google Scholar 

  35. Samii M, Gerganov V, Samii A (2006) Improved preservation of hearing and facial nerve function in vestibular schwannoma surgery via the retrosigmoid approach in a series of 200 patients. J Neurosurg 105:527–535

    PubMed  Google Scholar 

  36. Sells JP, Hurley RM (1994) Acoustic neuroma in an adolescent without neurofibromatosis: case study. J Am Acad Audiol 5:349–354

    PubMed  CAS  Google Scholar 

  37. Tos M, Thomsen J (1984) Epidemiology of acoustic neuromas. J Laryngol Otol 98:685–692

    PubMed  CAS  Google Scholar 

  38. Tos M, Stangerup SE, Caye-Thomasen P, Tos T, Thomsen J (2004) What is the real incidence of vestibular schwannoma? Arch Otolaryngol Head Neck Surg 130:216–220

    Article  PubMed  Google Scholar 

  39. Vassilouthis J, Richardson AE (1979) Acoustic neurinoma in a child. Surg Neurol 12:37–39

    PubMed  CAS  Google Scholar 

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Correspondence to Venelin M. Gerganov.

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Mirzayan, M.J., Gerganov, V.M., Lüdemann, W. et al. Management of vestibular schwannomas in young patients—comparison of clinical features and outcome with adult patients. Childs Nerv Syst 23, 891–895 (2007). https://doi.org/10.1007/s00381-007-0308-7

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  • DOI: https://doi.org/10.1007/s00381-007-0308-7

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