Abstract
Successful short-term implementation of nickel-titanium (NiTi) alloys as implants has been a motivation for the development of long-term applications. However, rendering these as safe implant materials is challenging. The major problem associated with the use of NiTi for in-vivo applications is the potential risk of Ni release from the implant surface due to the corrosive environment of the body. Various methods including surface treatment techniques with acid and alkali solutions and application of biocompatible coatings have been used to overcome these difficulties. In particular, NaOH pre-treatment has been commonly performed for surface activation of the substrate material to enhance the adhesion properties of coatings. The present work investigates the effect of NaOH pre-treatment on the hydroxyapatite (HA) coating and the resulting corrosion behavior of and cell response to HA coated NiTi wires. Microstructural examinations showed that the coating integrity deteriorated with prior NaOH treatment which also increased the corrosion rate as evidenced by potentiodynamic measurements. XPS analysis revealed heightened Ni levels on the sample surfaces and cytotoxicity tests showed decreased cell viability for the samples with pre-treatment. Absence of NaOH pre-treatment led to lower contact angle values pointing to higher biocompatibility.
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References
H.F. Li, F.L. Nie, Y.F. Zheng, Y. Cheng, S.C. Wei, R.Z. Valiev, Nanocrystalline Ti49.2Ni50.8 shape memory alloy as orthopaedic implant material with better performance. J. Mater. Sci. Technol. 35, 2156–2162 (2019). https://doi.org/10.1016/j.jmst.2019.04.026
C.H. NG, C.W. Chan, H.C. Man, D.G. Waugh, J. Lawrence, NiTi shape memory alloy with enhanced wear performance by laser selective area nitriding for orthopaedic applications. Surf. Coat. Technol. 309, 1015–1022 (2017). https://doi.org/10.1016/j.surfcoat.2016.10.042
H. Li, Y. Mao, X. Qu, X. Zhao, K. Dai, Z. Zhu, Nickel-titanium shape-memory sawtooth-arm embracing clamp for complex femoral revision hip arthroplasty. J. Arthroplasty. 31, 850–856 (2016). https://doi.org/10.1016/j.arth.2015.10.044
N. Pandis, C.P. Bourauel, Nickel-Titanium (NiTi) Arch Wires: The Clinical Significance of Super Elasticity. Semin. Orthod. 16, 249–257 (2010). https://doi.org/10.1053/j.sodo.2010.06.003
D.S. Levi, N. Kusnezov, G.P. Carman, Smart materials applications for pediatric cardiovascular devices. Pediatr. Res. 63, 552–558 (2008). https://doi.org/10.1203/PDR.0b013e31816a9d18
A.T. Tung, B.H. Park, A. Koolwal, B. Nelson, G. Niemeyer, D. Liang, Design and fabrication of tubular shape memory alloy actuators for active catheters. First. IEEE/RAS-EMBS. Int. Conf. Biomed. Robot. Biomechatron. (2006). https://doi.org/10.1109/BIOROB.2006.1639184
K. Otsuka, C.M. Wayman, Shape memory materials (Cambridge University Press, Cambridge, 1999), pp. 27–48
X. Wang, F. Liu, Y. Song, Enhanced corrosion resistance and in vitro bioactivity of NiTi alloys modified with hydroxyapatite-containing Al2O3 coatings. Surf. Coat. Technol. 344, 288–294 (2018). https://doi.org/10.1016/j.surfcoat.2018.03.034
M. Jamesh, S. Kumar, T.S.N. Sankara Narayanan, Electrodeposition of hydroxyapatite coating on magnesium for biomedical applications. J. Coat. Technol. Res. 9, 495–502 (2012). https://doi.org/10.1007/s11998-011-9382-6
C.F. Dunne, K. Roche, B. Twomey, K.T. Stanton, Deposition of hydroxyapatite onto shape memory NiTi wire. Mater. Lett. 176, 185–188 (2016). https://doi.org/10.1016/j.matlet.2016.04.074
Q. Bao, K. Zhao, J. Liu, Characterization of wollastonite coatings prepared by sol–gel on Ti substrate. J. Coat. Technol. Res. 9, 189–193 (2012). https://doi.org/10.1007/s11998-009-9236-7
A. Carradò, Nano-crystalline pulsed laser deposition hydroxyapatite thin films on Ti substrate for biomedical application. J. Coat. Technol. Res. 8, 749 (2011). https://doi.org/10.1007/s11998-011-9355-9
J. Choi, D. Bogdanski, M. Köller, S.A. Esenwein, D. Müller, G. Muhr, M. Epple, Calcium phosphate coating of nickel–titanium shape-memory alloys. Coating procedure and adherence of leukocytes and platelets. Biomaterials 24, 3689–3696 (2003). https://doi.org/10.1016/S0142-9612(03)00241-2
B. Aksakal, C. Hanyaloglu, Bioceramic dip-coating on Ti–6Al–4V and 316L SS implant materials. J. Mater. Sci. Mater Med. 19, 2097–2104 (2008). https://doi.org/10.1007/s10856-007-3304-2
X. Liu, P.K. Chu, C. Ding, Surface modification of titanium, titanium alloys, and related materials for biomedical applications. Mater. Sci. Eng. R Reports. 47, 49–121 (2004). https://doi.org/10.1016/j.mser.2004.11.001
W. Qiang, C. Zhen-duo, Y. Xian-jin, S. Jie, Improving the bioactivity of NiTi shape memory alloy by heat and alkali treatment. Appl. Surf. Sci. 255, 462–465 (2008). https://doi.org/10.1016/j.apsusc.2008.06.069
H.M. Kim, F. Miyaji, T. Kokubo, T. Nakamura, Effect of heat treatment on apatite-forming ability of Ti metal induced by alkali treatment. J. Mater. Sci. Mater. Med. 8, 341–347 (1997). https://doi.org/10.1023/a:1018524731409
P. Li, I. Kangasniemi, K. Groot, T. Kokubo, Bonelike hydroxyapatite induction by a gel-derived titania on a titanium substrate. J. Am. Ceram. Soc. 5, 1307–1312 (1994). https://doi.org/10.1111/j.1151-2916.1994.tb05407.x
L. Jonášová, F.A. Müller, A. Helebrant, J. Strnad, P. Greil, Hydroxyapatite formation on alkali-treated titanium with different content of Na+ in the surface layer. Biomaterials 23, 3095–3101 (2002). https://doi.org/10.1016/S0142-9612(02)00043-1
H. Takadama, H.M. Kim, T. Kokubo, T. Nakamura, TEM-EDX study of mechanism of bonelike apatite formation on bioactive titanium metal in simulated body fluid. J. Biomed. Mater. Res. 57, 441–448 (2001). https://doi.org/10.1002/1097-4636(20011205)57:3<441:aid-jbm1187>3.0.co;2-b
W. Chrzanowski, E.A. Abou-Neel, D.A. Armitage, J.C. Knowles, Surface preparation of bioactive NiTi alloy using alkali, thermal-treatments and spark oxidation. J. Mater. Sci: Mater. Med. 19, 1553–1557 (2008). https://doi.org/10.1007/s10856-008-3374-9
W. Chrzanowski, E.A. Abou-Neel, D.A. Armitage, K. Lee, W. Walke, J.C. Knowles, Nanomechanical evaluation of nickel-titanium surface properties after alkali and electrochemical treatments. J. R. Soc. Interface 5, 1009–1022 (2008). https://doi.org/10.1098/rsif.2007.1313
M. Wei, A.J. Ruys, B.K. Milthorpe, C.C. Sorrell, J.H. Evans, Electrophoretic deposition of hydroxyapatite coatings on metal substrates: a nanoparticulate dual-coating approach. J. Sol-Gel. Sci. Technol. 21, 39–48 (2001). https://doi.org/10.1023/A:1011201414651
L.A. Sena, M.C. Andrade, A.M. Rossi, G.A. Soares, Hydroxyapatite deposition by electrophoresis on titanium sheets with different surface finishing. J. Biomed. Mater. Res. 60, 1–7 (2002). https://doi.org/10.1002/jbm.10003
International organization for standardization (ISO) 109993–5:2009, Biological evaluation of medical devices - Part 5: tests for in vitro cytotoxicity
M. Sandhyarani, T. Prasadrao, N. Rameshbabu, Role of electrolyte composition on structural, morphological and in-vitro biological properties of plasma electrolytic oxidation films formed on zirconium. Appl. Surf. Sci. 317, 198–209 (2014). https://doi.org/10.1016/j.apsusc.2014.08.081
Y. Han, D. Chen, J. Sun, Y. Zhang, K. Xu, UV-enhanced bioactivity and cell response of micro-arc oxidized titania coatings. Acta. Biomater. 4, 1518–1529 (2008). https://doi.org/10.1016/j.actbio.2008.03.005
D. Aronov, G. Rosenman, Wettability study of modified silicon dioxide surface using environmental scanning electron microscopy. J. Appl. Phys. 101, 084901–084901 (2007). https://doi.org/10.1063/1.2721945
S. Kapila, R. Sachdeva, Mechanical properties and clinical applications of orthodontic wires. Am. J. Orthod. Detofac. Orthop. 96, 100–109 (1989). https://doi.org/10.1016/0889-5406(89)90251-5
Z. Laster, A.D. MacBean, P.R. Ayliffe, L.C. Newlands, Fixation of a frontozygomatic fracture with a shape-memory staple. Br. J. Oral Maxillofac. Surg. 39, 324–325 (2001). https://doi.org/10.1054/bjom.2001.0633
M.F. Chen, X.J. Yang, R.X. Hu, Z.D. Cui, H.C. Man, Bioactive NiTi shape memory alloy used as bone bonding implants. Mater. Sci. Eng. C. 24, 497–502 (2004). https://doi.org/10.1016/j.msec.2003.11.001
T.M. Sridhar, U. Kamachi Mudali, M. Subbaiyan, Sintering atmosphere and temperature effects on hydroxyapatite coated type 316L stainless steel. Corros. Sci. 45, 2337–2359 (2003). https://doi.org/10.1016/S0010-938X(03)00063-5
S.A. Shabalovskaya, J. Anderegg, F. Laab, P.A. Thiel, G. Rondelli, Surface conditions of Nitinol wires, tubing, and as-cast alloys. The effect of chemical etching, aging in boiling water, and heat treatment. J. Biomed. Mater. Res. B Appl. Biomater. 65, 193–203 (2003). https://doi.org/10.1002/jbm.b.10001
S. Wu, X. Liu, Y.L. Chan et al., Nickel release behavior, cytocompatibility, and superelasticity of oxidized porous single-phase NiTi. J. Biomed. Mater. Res. A. 81, 948–955 (2007). https://doi.org/10.1002/jbm.a.31115
H.H. Huang, Y.H. Chiu, T.H. Lee, S.C. Wu, H.W. Yang, K.H. Su, C.C. Hsu, Ion release from NiTi orthodontic wires in artificial saliva with various acidities. Biomaterials 24, 3585–3592 (2003). https://doi.org/10.1016/S0142-9612(03)00188-1
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The authors would like to acknowledge Ozyegin University for the financial support throughout this study.
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Simsek, G.M., Ipekoglu, M. & Yapici, G.G. Evaluation of NaOH pre-treatment on the corrosion behavior and surface characteristics of hydroxyapatite coated NiTi alloy. Appl. Phys. A 126, 659 (2020). https://doi.org/10.1007/s00339-020-03847-1
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DOI: https://doi.org/10.1007/s00339-020-03847-1