Abstract
Background
Bone defect around the femur related to revisions or periprosthetic fractures (PFF) is an issue. We present a bone defect reconstruction technique in femoral revisions and/or PFF using fibula autograft and compared our radiological and clinical results to that of allograft.
Methods
A total of 53 patients who underwent revision hip arthroplasty and/or PFF fixation with the use of cortical fibula autograft (FG group) or cortical allograft (CG group) were evaluated. After exclusions, 20 patients who had minimum two years of follow-up were investigated for each group, for their radiological and clinical outcomes.
Results
In FG and CG groups, the median ages were 69.5(44–90) and 62(38–88) years, follow-ups were 59(28–72) and 120(48–216) months, defect lengths were seven (1–10) and ten (1–17) cm, and grafts lengths were 16.5(10–30) and 20(12–37) cm, respectively. The rate of graft incorporation was 90% in each group and median time to incorporations were seven (4–12) and 12(6–24) months (p < 0.001), and graft resorption (moderate and severe) rates were 10% and 25% (p = 0.41), respectively. Median Harris Hip (77.6 vs 78.0), WOMAC (23.2 vs 22), SF-12 physical (50.0 vs 46.1), and SF-12 mental (53.8 vs 52.5) scores were similar between the groups, respectively. Kaplan–Meier survivorship analyses revealed an estimated mean survival of 100% at six years in FG group and 90% at 14 years in CG group.
Conclusion
In the reconstruction of periprosthetic bone defects after femoral revision or PPF, onlay cortical fibula autografts provide comparable clinical and radiological outcomes to allografts. Its incorporation is faster, it is cost-effective and easy to obtain without apparent morbidity.
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References
Kurtz S, Mowat F, Ong K, Chan N, Lau E, Halpern M (2005) Prevalence of primary and revision total hip and knee arthroplasty in the United States from 1990 through 2002. J Bone Joint Surg Am 87:1487–1497. https://doi.org/10.2106/JBJS.D.02441
Kurtz SM, Ong KL, Schmier J, Mowat F, Saleh K, Dybvik E, Karrholm J, Garellick G, Havelin LI, Furnes O, Malchau H, Lau E (2007) Future clinical and economic impact of revision total hip and knee arthroplasty. J Bone Joint Surg Am 89(Suppl 3):144–151. https://doi.org/10.2106/JBJS.G.00587
Wroblewski BM (1984) Current trends in revision of total hip arthroplasty. Int Orthop 8:89–93. https://doi.org/10.1007/BF00265830
Ong A, Wong KL, Lai M, Garino JP, Steinberg ME (2002) Early failure of precoated femoral components in primary total hip arthroplasty. J Bone Joint Surg Am 84:786–792. https://doi.org/10.2106/00004623-200205000-00014
Phillips CB, Barrett JA, Losina E, Mahomed NN, Lingard EA, Guadagnoli E, Baron JA, Harris WH, Poss R, Katz JN (2003) Incidence rates of dislocation, pulmonary embolism, and deep infection during the first six months after elective total hip replacement. J Bone Joint Surg Am 85:20–26. https://doi.org/10.2106/00004623-200301000-00004
Parvizi J, Wade FA, Rapuri V, Springer BD, Berry DJ, Hozack WJ (2006) Revision hip arthroplasty for late instability secondary to polyethylene wear. Clin Orthop Relat Res 447:66–69. https://doi.org/10.1097/01.blo.0000218751.14989.a6
Jafari SM, Coyle C, Mortazavi SM, Sharkey PF, Parvizi J (2010) Revision hip arthroplasty: infection is the most common cause of failure. Clin Orthop Relat Res 468:2046–2051. https://doi.org/10.1007/s11999-010-1251-6
Ulrich SD, Seyler TM, Bennett D, Delanois RE, Saleh KJ, Thongtrangan I, Kuskowski M, Cheng EY, Sharkey PF, Parvizi J, Stiehl JB, Mont MA (2008) Total hip arthroplasties: what are the reasons for revision? Int Orthop 32:597–604. https://doi.org/10.1007/s00264-007-0364-3
Kuijpers MFL, Hannink G, Vehmeijer SBW, van Steenbergen LN, Schreurs BW (2019) The risk of revision after total hip arthroplasty in young patients depends on surgical approach, femoral head size and bearing type; an analysis of 19,682 operations in the Dutch arthroplasty register. BMC Musculoskelet Disord 20:385. https://doi.org/10.1186/s12891-019-2765-z
Schmitz MW, Busch VJ, Gardeniers JW, Hendriks JC, Veth RP, Schreurs BW (2013) Long-term results of cemented total hip arthroplasty in patients younger than 30 years and the outcome of subsequent revisions. BMC Musculoskelet Disord 14:37. https://doi.org/10.1186/1471-2474-14-37
Gustilo RB, Pasternak H (1988) Revision total hip arthroplasty with titanium ingrowth prosthesis and bone grafting for failed cemented femoral component loosening. Clin Orthop Relat Res 235:111–9
Kavanagh BF, Ilstrup D, Fitzgerald RH Jr (1985) Revision total hip arthroplasty. J Bone Joint Surg Am 67(4):517
Maloney WJ, Jasty M, Rosenberg A et al (1990) Bone lysis in well-fixed cemented femoral components. J Bone Joint Surg (Br) 72(6):966
Gruen TA, McNeice G, Amstutz HC (1979) “Modes of failure” of cemented stem-type femoral components: a radiographic analysis of loosening. Clin Orthop Relat Res 141:17–27
Crockarell JR Jr, Berry DJ, Lewallen DG (1999) Nonunion after periprosthetic femoral fracture associated with total hip arthroplasty. J Bone Joint Surg Am 81:1073–1079. https://doi.org/10.2106/00004623-199908000-00003
Randelli F, Pace F, Priano D, Giai Via A, Randelli P (2018) Re-fractures after periprosthetic femoral fracture: a difficult to treat growing evidence. Injury 49(Suppl 3):S43–S47. https://doi.org/10.1016/j.injury.2018.09.045
Arealis G, Nikolaou VS, Lacon A, Ashwood N, Hamlet M (2014) Plate on plate osteosynthesis for the treatment of nonhealed periplate fractures. ISRN Orthop 2014:367490. https://doi.org/10.1155/2014/367490
Emerson RH Jr, Malinin T, Cuellar AD, Head WC, Peters PC (1992) Cortical strut allografts in the reconstruction of the femur in revision total hip arthroplasty. A basic science and clinical study. Clin Orthop Relat Res 285:35–44
Gross AE, Lavoie M, McDermott P et al (1985) The use of allograft bone in revision of total hip arthroplasty. Clin Orthop Relat Res 197:115–122
Head WC, Malinin T, Mallory TH et al (1998) Onlay cortical allografting for the femur. Orthop Clin North Am 29:307–312
Head WC, Wagner R, Emerson RH et al (1993) Restoration of femoral bone stock in revision total hip arthroplasty. Orthop Clin North Am 24:697–703
Chandler HP, King D, Limbird R et al (1993) The use of cortical allograft struts for fixation of fractures associated with well-fixed total joint prostheses. Semin Arthroplast 4:99–107
Kim YH, Park JW, Kim JS, Rastogi D (2015) High survivorship with cementless stems and cortical strut allografts for large femoral bone defects in revision THA. Clin Orthop Relat Res 473:2990–3000. https://doi.org/10.1007/s11999-015-4358-y
Fishman JA, Greenwald MA, Grossi PA (2012) Transmission of infection with human allografts: essential considerations in donor screening. Clin Infect Dis 55:720–727. https://doi.org/10.1093/cid/cis519
Ng VY (2012) Risk of disease transmission with bone allograft. Orthopedics 35:679–681. https://doi.org/10.3928/01477447-20120725-04
Mankin HJ, Hornicek FJ, Raskin KA (2005) Infection in massive bone allografts. Clin Orthop Relat Res:210–216. https://doi.org/10.1097/01.blo.0000150371.77314.52
Walter M (1911) Resection de l’extremite inferieure du radius pour osteosarcome: greffe de l’extremité supériuie du péroné. Bull mém Soc chir Paris 37:739–747
Liu S, Tao S, Tan J, Hu X, Liu H, Li Z (2018) Long-term follow-up of fibular graft for the reconstruction of bone defects. Medicine (Baltimore) 97:e12605. https://doi.org/10.1097/MD.0000000000012605
Swamy MK, Rathi A, Gupta V (2013) Results of non-vascularised fibular grafting in gap non-union of long bones in paediatric age group. J Clin Orthop Trauma 4:180–184. https://doi.org/10.1016/j.jcot.2013.09.001
Dell PC, Burchardt H, Glowczewskie FP Jr (1985) A roentgenographic, biomechanical, and histological evaluation of vascularized and non-vascularized segmental fibular canine autografts. J Bone Joint Surg Am 67-A:105–112
Duncan CP, Masri B (1995) Fractures of the femur after hip replacement. Instr Course Lect 45:293–304
Aribindi R, Barba M, Solomon MI, Arp P, Paprosky W (1998) Bypass fixation. Orthop Clin North Am. 29(2):319–29. https://doi.org/10.1016/s0030-5898(05)70330-8
Kim YH, Franks D (1992) Cementless revision of cemented stem failures associated with massive femoral bone loss: a technical note. Orthop Rev 21:375–380
Fernyhough JC, White JONI, Larocca H (1991) Fusion rates in multilevel cervical spondylosis comparing allograft fibula with autograft fibula in 126 patients. Spine J 16:10
Faldini C, Traina F, Perna F, Borghi R, Nanni M, Chehrassan M (2015) Surgical treatment of aseptic forearm nonunion with plate and opposite bone graft strut. Autograft or allograft? Int Orthop 39:1343–1349. https://doi.org/10.1007/s00264-015-2718-6
Barden B, von Knoch M, Fitzek JG, Loer F (2003) Periprosthetic fractures with extensive bone loss treated with onlay strut allografts. Int Orthop 27:164–167. https://doi.org/10.1007/s00264-002-0423-8
Sariyilmaz K, Dikici F, Dikmen G, Bozdag E, Sunbuloglu E, Bekler B, Yazicioglu O (2014) The effect of strut allograft and its position on Vancouver type B1 periprosthetic femoral fractures: a biomechanical study. J Arthroplast 29:1485–1490. https://doi.org/10.1016/j.arth.2014.02.017
Fakhri RM, Herard P, Liswi MI, Boulart AL, Al Ani AMK (2019) Decision-making algorithm for sequential treatment of diaphyseal bone gaps in war-wounded patients in the Middle East. Int Orthop 43:2653–2659. https://doi.org/10.1007/s00264-019-04317-x
Jamshidi K, Mirkazemi M, Izanloo A, Mirzaei A (2018) Locking plate and fibular strut-graft augmentation in the reconstruction of unicameral bone cyst of proximal femur in the paediatric population. Int Orthop 42:169–174. https://doi.org/10.1007/s00264-017-3648-2
Lochab J, Carrothers A, Wong E, McLachlin S, Aldebeyan W, Jenkinson R, Whyne C, Nousiainen MT (2017) Do transcortical screws in a locking plate construct improve the stiffness in the fixation of Vancouver B1 periprosthetic femur fractures? A biomechanical analysis of 2 different plating constructs. J Orthop Trauma 31:15–20. https://doi.org/10.1097/BOT.0000000000000704
Ogden WS, Rendall J (1978) Fractures beneath hip prostheses: a special indication for Parham bands and plating. Orthop Trans 2:70
Lenz M, Stoffel K, Gueorguiev B, Klos K, Kielstein H, Hofmann GO (2016) Enhancing fixation strength in periprosthetic femur fractures by orthogonal plating-a biomechanical study. J Orthop Res 34:591–596. https://doi.org/10.1002/jor.23065
Moazen M, Mak JH, Etchels LW, Jin Z, Wilcox RK, Jones AC, Tsiridis E (2014) Periprosthetic femoral fracture--a biomechanical comparison between Vancouver type B1 and B2 fixation methods. J Arthroplast 29:495–500. https://doi.org/10.1016/j.arth.2013.08.010
Fulkerson E, Koval K, Preston CF, Iesaka K, Kummer FJ, Egol KA (2006) Fixation of periprosthetic femoral shaft fractures associated with cemented femoral stems: a biomechanical comparison of locked plating and conventional cable plates. J Orthop Trauma 20:89–93. https://doi.org/10.1097/01.bot.0000199119.38359.96
Fulkerson E, Egol KA, Kubiak EN, Liporace F, Kummer FJ, Koval KJ (2006) Fixation of diaphyseal fractures with a segmental defect: a biomechanical comparison of locked and conventional plating techniques. J Trauma 60:830–835. https://doi.org/10.1097/01.ta.0000195462.53525.0c
Zdero R, Walker R, Waddell JP, Schemitsch EH (2008) Biomechanical evaluation of periprosthetic femoral fracture fixation. J Bone Joint Surg Am 90:1068–1077. https://doi.org/10.2106/JBJS.F.01561
Lindahl H, Malchau H, Oden A, Garellick G (2006) Risk factors for failure after treatment of a periprosthetic fracture of the femur. J Bone Joint Surg (Br) 88:26–30. https://doi.org/10.1302/0301-620X.88B1.17029
Agarwal A (2019) Fibular donor site following non vascularized harvest: clinico-radiological outcome at minimal five year follow-up. Int Orthop 43:1927–1931. https://doi.org/10.1007/s00264-018-4086-5
Nassr A, Khan MH, Ali MH, Espiritu MT, Hanks SE, Lee JY, Donaldson WF, Kang JD (2009) Donor-site complications of autogenous nonvascularized fibula strut graft harvest for anterior cervical corpectomy and fusion surgery: experience with 163 consecutive cases. Spine J 9:893–898. https://doi.org/10.1016/j.spinee.2009.04.020
Owen H, Brady DSG, Masri BA, Duncan CP (1999) The treatment of periprosthetic fractures of the femur using cortical onlay allograft struts. Orthop Clin N Am 30:2
Pala E, Trovarelli G, Calabro T, Angelini A, Abati CN, Ruggieri P (2015) Survival of modern knee tumor megaprostheses: failures, functional results, and a comparative statistical analysis. Clin Orthop Relat Res 473:891–899. https://doi.org/10.1007/s11999-014-3699-2
Sevelda F, Schuh R, Hofstaetter JG, Schinhan M, Windhager R, Funovics PT (2015) Total femur replacement after tumor resection: limb salvage usually achieved but complications and failures are common. Clin Orthop Relat Res 473:2079–2087. https://doi.org/10.1007/s11999-015-4282-1
Capanna R, Scoccianti G, Frenos F, Vilardi A, Beltrami G, Campanacci DA (2015) What was the survival of megaprostheses in lower limb reconstructions after tumor resections? Clin Orthop Relat Res 473:820–830. https://doi.org/10.1007/s11999-014-3736-1
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This retrospective study was approved by the institutional review board (45446446-010.99-5866).
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Patients who were reconstructed with fibular autograft were applied in Bezmialem Vakif University Hospital, and patients who were reconstructed with cortical allograft were applied in Acibadem Maslak Hospital.
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Tuncay, İ., Tözün, R., Aliyev, O. et al. Onlay fibula autografting technique and its comparison with cortical allograft for the reconstruction of periprosthetic bone defects around the femur. International Orthopaedics (SICOT) 45, 71–81 (2021). https://doi.org/10.1007/s00264-020-04876-4
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DOI: https://doi.org/10.1007/s00264-020-04876-4