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Massoia Lactone Displays Strong Antifungal Property Against Many Crop Pathogens and Its Potential Application

  • Fungal Microbiology
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Abstract

Massoia lactone could be released from liamocins produced by Aureobasidium melanogenum M39. The obtained Massoia lactone was very stable and highly active against many fungal crop pathogens which cause many plant diseases and food unsafety. Massoia lactone treatment not only could effectively inhibit their hyphal growth and spore germination, but also caused pore formation in cell membrane, reduction of ergosterol content, rise in intracellular ROS levels, and leakage of intracellular components, consequently leading to cellular necrosis and cell death. The direct contact of Massoia lactone with Fusarium graminearum spores could stop the development of Fusarium head blight symptom in the diseased wheats. Therefore, Massoia lactone could be a promising candidate for development as an effective and green bio-fungicide because of its high anti-fungal activity and the multiplicity of mode of its action.

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Data Availability

All data generated or analyzed during this study are included in this published article (and its supplementary information files).

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Funding

This study was financially supported by the National Natural Science Foundation of China (Grant No. 31970058), the key research and development of Shandong Province (Grant No. 2019GSF107097), Bingtuan Science and Technology Program (Grant No. 2021BC009), and the Fundamental Research Funds for the Central Universities (Grant No. 202066002).

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Author notes

  1. Mei Zhang and Zhi-Chao Gao made equal contribution to this study.

Authors and Affiliations

  1. College of Marine Life Science, Ocean University of China, Yushan Road, No. 5, Qingdao, China

    Mei Zhang, Zhi-Chao Gao, Zhe Chi, Zhu Wang, Guang-Lei Liu & Zhen-Ming Chi

  2. Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, 266003, China

    Zhe Chi, Guang-Lei Liu & Zhen-Ming Chi

  3. State Key Laboratory of Crop Biology, Shandong Key Laboratory of Crop Biology, College of Agronomy, Shandong Agriculture University, Tai’an, 271018, China

    Xue-Feng Li

  4. Department of Biology, Shantou University, Shantou, 515063, China

    Zhong Hu

Authors
  1. Mei Zhang
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  3. Zhe Chi
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  4. Zhu Wang
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Contributions

MZ, ZCG, ZW, and XFL conducted all the experiments. ZC and GLL analyzed data. ZH and ZMC conceived and designed research and wrote the manuscript. All authors read and approved the manuscript.

Corresponding author

Correspondence to Zhen-Ming Chi.

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Zhang, M., Gao, ZC., Chi, Z. et al. Massoia Lactone Displays Strong Antifungal Property Against Many Crop Pathogens and Its Potential Application. Microb Ecol 84, 376–390 (2022). https://doi.org/10.1007/s00248-021-01885-7

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  • DOI: https://doi.org/10.1007/s00248-021-01885-7

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