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Oxidative stress: from modification of cell-cycle related events, secondary messenger function, dysregulation of small GTPases, protein kinases and phosphatases to redox-sensitive cancer models

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References

  • Barbosa F Jr, Sertorio JT, Gerlach RF, Tanus-Santos JE (2006) Clinical evidence for lead-induced inhibition of nitric oxide formation. Arch Toxicol 80:811–816

    Article  PubMed  CAS  Google Scholar 

  • Bolt HM, Hengstler JG (2008) The past and the future of toxicology. Arch Toxicol 82:1–3

    Article  PubMed  CAS  Google Scholar 

  • Furuyama A, Hirano S, Koike E, Kobayashi T (2006) Induction of oxidative stress and inhibition of plasminogen activator inhibitor-1 production in endothelial cells following exposure to organic extracts of diesel exhaust particles and urban fine particles. Arch Toxicol 80:154–162

    Article  PubMed  CAS  Google Scholar 

  • Hengstler JG, Bolt HM (2007) Induction and control of oxidative stress. Arch Toxicol 81:823–824

    Article  PubMed  CAS  Google Scholar 

  • Hengstler JG, Bolt HM (2008) Loss of DNA damage checkpoint genes: switch from preferential induction of point mutations to chromosomal damage precedes the transition towards an aggressive cancer type. Arch Toxicol (in press)

  • Hengstler JG, Bogdanffy MS, Bolt HM, Oesch F (2003) Challenging dogma: thresholds for genotoxic carcinogens? The case of vinyl acetate. Annu Rev Pharmacol Toxicol 43:485–520

    Article  PubMed  CAS  Google Scholar 

  • Kashida Y, Takahashi A, Moto M, Okamura M, Muguruma M, Jin M, Arai K, Mitsumori K (2006) Gene expression analysis in mice liver on hepatocarcinogenesis by flumequine. Arch Toxicol 80:533–539

    Article  PubMed  CAS  Google Scholar 

  • Korkmaz A, Yaren H, Topal T, Oter S (2006) Molecular targets against mustard toxicity: implication of cell surface receptors, peroxynitrite production, and PARP activation. Arch Toxicol 80:662–670

    Article  PubMed  CAS  Google Scholar 

  • Lee JS, Kim SY, Kwon CH, Kim YK (2006) EGFR-dependent ERK activation triggers hydrogen peroxide-induced apoptosis in OK renal epithelial cells. Arch Toxicol 80:337–346

    Article  PubMed  CAS  Google Scholar 

  • Lee HS, Jung SH, Yun BS, Lee KW (2007) Isolation of chebulic acid from Terminalia chebula Retz. and its antioxidant effect in isolated rat hepatocytes. Arch Toxicol 81:211–218

    Article  PubMed  CAS  Google Scholar 

  • Lilienblum W, Dekant W, Foth H, Gebel T, Hengstler JG, Kahl R, Kramer PJ, Schweinfurth H, Wollin KM (2008) Alternative methods to safety studies in experimental animals: role in the risk assessment of chemicals under the new European Chemicals Legislation (REACH). Arch Toxicol (in press)

  • Mátes et al. (2008) Intracellular redox status and oxidative stress: implications for cell proliferation, apoptosis and carcinogenesis. Arch Toxicol (in press)

  • M’Bemba-Meka P, Lemieux N, Chakrabarti SK (2006a) Role of oxidative stress, mitochondrial membrane potential, and calcium homeostasis in human lymphocyte death induced by nickel carbonate hydroxide in vitro. Arch Toxicol 80:405–420

    Article  PubMed  CAS  Google Scholar 

  • M’Bemba-Meka P, Lemieux N, Chakrabarti SK (2006b) Role of oxidative stress, mitochondrial membrane potential, and calcium homeostasis in human lymphocyte death induced by nickel carbonate hydroxide in vitro. Arch Toxicol (in press)

  • M’Bemba-Meka P, Lemieux N, Chakrabarti SK (2007) Role of oxidative stress and intracellular calcium in nickel carbonate hydroxide-induced sister-chromatid exchange, and alterations in replication index and mitotic index in cultured human peripheral blood lymphocytes. Arch Toxicol 81:89–99

    Article  PubMed  CAS  Google Scholar 

  • Moto M, Umemura T, Okamura M, Muguruma M, Ito T, Jin M, Kashida Y, Mitsumori K (2006) Possible involvement of oxidative stress in dicyclanil-induced hepatocarcinogenesis in mice. Arch Toxicol 80:694–702

    Article  PubMed  CAS  Google Scholar 

  • Nampoothiri LP, Agarwal A, Gupta S (2007) Effect of co-exposure to lead and cadmium on antioxidant status in rat ovarian granulose cells. Arch Toxicol 81:145–150

    Article  PubMed  CAS  Google Scholar 

  • Periyakaruppan A, Kumar F, Sarkar S, Sharma CS, Ramesh GT (2007) Uranium induces oxidative stress in lung epithelial cells. Arch Toxicol 81:389–395

    Article  PubMed  CAS  Google Scholar 

  • Tanaka M, Chock PB, Stadtman ER (2007) Oxidized messenger RNA induces translation errors. PNAS 104:66–71

    Article  PubMed  CAS  Google Scholar 

  • Tomita M, Okuyama T, Katsuyama H, Ishikawa T (2006) Paraquat-induced gene expression in rat kidney. Arch Toxicol 80:687–693

    Article  PubMed  CAS  Google Scholar 

  • Venkatesh S, Kavitha ML, Zachariah A, Oommen A (2006) Progression of type I to type II paralysis in acute organophosphorous poisoning: is oxidative stress significant? Arch Toxicol 80:354–361

    Article  PubMed  CAS  Google Scholar 

  • Zhan XA, Wang M, Xu ZR, Li WF, Li JX (2006) Evaluation of caspase-dependent apoptosis during fluoride-induced liver lesion in pigs. Arch Toxicol 80:74–80

    Article  PubMed  CAS  Google Scholar 

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Correspondence to J. G. Hengstler.

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Hengstler, J.G., Bolt, H.M. Oxidative stress: from modification of cell-cycle related events, secondary messenger function, dysregulation of small GTPases, protein kinases and phosphatases to redox-sensitive cancer models. Arch Toxicol 82, 271–272 (2008). https://doi.org/10.1007/s00204-008-0305-y

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