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Loss of DNA damage checkpoint genes: switch from preferential induction of point mutations to chromosomal damage precedes the transition towards an aggressive cancer type

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Authors and Affiliations

  1. Institut für Arbeitsphysiologie an der Universität Dortmund, Leibniz Research Center for Working Environment and Human Factors (IfADo), Ardeystrasse 67, 44139, Dortmund, Germany

    J. G. Hengstler & H. M. Bolt

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  1. J. G. Hengstler
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  2. H. M. Bolt
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Correspondence to J. G. Hengstler.

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Hengstler, J.G., Bolt, H.M. Loss of DNA damage checkpoint genes: switch from preferential induction of point mutations to chromosomal damage precedes the transition towards an aggressive cancer type. Arch Toxicol 82, 341–342 (2008). https://doi.org/10.1007/s00204-008-0295-9

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