Patellofemoral disorders after TKA are frequent and might be associated with the change in joint articulation morphology. Herein, trochlear groove geometries of 33 patients were examined intraoperatively via tactile scanning before and after implantation of a bicondylar total knee replacement without radiation exposure to characterize the geometric key parameters SH as well as medCH and latCH. The main finding was that despite the use of a modern bicondylar total knee endoprosthesis, the artificial joint articulation morphology has a differently shaped contour. Changes in patellofemoral morphology may alter knee joint dynamics, e.g., a thicker anterior shield leads to increased patellofemoral contact force.
This feasibility study showed distinct alterations in the investigated parameters SH, medCH, and latCH due to TKA throughout the femoral anterior cortex. Concerning the SH, the total knee replacement caused an increase in the proximal portion of the trochlea and a decrease in the distal portion. Broadly similar and independent from implant size, the positive peak in ∆SH occurred between −30° and −15°, which was then followed by the negative peak at around +15°. This suggests that the total knee replacement implanted does not match the geometric contour of the natural trochlear groove. The results also showed that most patients (52%) had a medium change in SH due to TKA, which could be a potential contributor to anterior knee pain as previous studies stated [2, 16] that the anterior-posterior positioning of the femoral component is an important factor. Note, although it has been shown that there is a significant difference in knee joint kinematics between male and female [5, 8, 20], the calculated parameters of the trochlear groove showed similar results among genders as equally reported by several studies [7, 24, 34]. Therefore, distinction between male and female subjects was not done.
Varadarajan et al. [34] reported that the SH in knees after TKA was smaller than in natural knees almost over the whole range of their defined cutting planes; however, they investigated different implant designs, in which the SH may vary, and their study was solely simulative, which might lead to different results when compared to real TKA implantations. Du et al. [9] instead reported similar results to our study. Likewise, they observed that SH in natural knees is smaller than in endoprosthetic knees. The implications of altered SH are severe as they may affect knee flexion moment and patellofemoral joint forces [9]. A higher SH due to TKA leads to a higher retropatellar pressure as the findings of Steinbrueck et al. [29] showed, thus emphasizing the importance of this parameter. The absolute magnitudes of ∆SH, however, are not distinguishable due to high standard deviations within each group. We explain these high standard deviations with the variation of the quality and number of points intraoperatively obtained. Moreover, the natural geometry of the trochlear groove likely scatters with the patient population [9, 18]. Similar to previous studies [3, 14, 34], a great variation in the trochlear groove’s geometric parameters were observed for the native femora and could explain the high standard deviations in our study. Consequently, the alterations we observed in SH are expected to cause a change in the patellofemoral joint kinematics and presumably higher patellofemoral pressure. These biomechanical parameters are indeed associated with anterior knee pain. Moreover, alteration of the SH might change the position of the patella and therefore the lever arm of the extensor muscles leading to differences in joint forces [9, 31]. Similar to the SH, our results showed distinct alterations in the parameters medCH and latCH due to TKA. In general, the femoral condyles, particularly the medCH, were higher in native knees. Varadarajan et al. [34] reported that the condylar height tended to be reduced after TKA. These findings are partly inconsistent with the results of the presented study. In our study, we found a tendency for the latCH to be increased due to TKA. On the opposite, the medCH was decreased after TKA which agrees with Varadarajan et al. [34] but again, the investigated implant designs were different between the studies and real TKA might be different from the simulation. In particular, the medial condyle was higher in the native knee compared to the prosthetic knees, which might lead to medial luxation postoperatively.
Lozano et al. [19] investigated the influence of mechanically and kinematically aligned total knee implants on the trochlear groove anatomy respective to the native knee. In agreement with our results, they found that the geometry of the trochlear groove was changed after TKA, e.g. the SH was changed by up to 5 mm while we detected a maximum and minimum mean difference by around 2 mm and −3.06 mm, respectively. The classification of all 33 patients showed that despite significant differences between preoperative and postoperative patellofemoral morphology, the majority received good reconstruction of the femoral geometry with a medium change (2.5–5 mm) in the investigated parameters. This is in accordance with the good clinical results of the investigated implant system [6].
Regarding the accuracy of the tactile scanner and its intraoperative use, the recorded points closely sampled the actual implant surface within a mean error in the distance of 0.79 mm, and an average RMSE of 0.65 mm. Thus, the raw data of our study can be considered sufficiently accurate. Depending on the number of recorded points and their spatial distribution, the generated surface matched the real geometry accurately; however, our presented approach represents some limitations. Despite a standardized procedure to sample the femoral surface, the data could not be recorded in the same way for each subject. Therefore, the quality of the reconstructed surfaces varied and suffered from interpolation artefacts and lack of coverage, especially in the outer regions. Hence, for very low (trochlear groove) and very high (anterior cortex) cutting angles θ, the automated parameter extraction was not always reliable. For the sake of quality and reliability, reconstructed surfaces were double checked for every patient. The reason behind all these limitations is the slow manual point acquisition procedure during surgery, which could lead to variations between different surgeons. This limitation represents the trade-off between experimental cadaver studies [14, 31], computational studies [7, 9, 34], and intraoperative data capture in living subjects. For future studies, our method will be improved as it concerns the sample point acquisition during surgery. In the present study, the trochlear bisector angle and sulcus position were not evaluated, although they are important parameters in knee implant design and should be included in future investigations. As we examined only one total knee replacement, the results are limited to this endoprosthesis design and it is desirable to extend the study not only to more parameters but also to a greater variety of implant designs. Another limitation is that no clinical data has been used, therefore, different morphological parameters may be correlated to the clinical outcome using standardised procedures and scores like the Knee Society Score or Oxford Knee Score in future studies [15]. Furthermore, the effect of implant positioning on the morphological key parameters of the patellofemoral joint should be analyzed in future studies as previously conducted by Lozano et al. [19].
Our study aimed to establish a method to intraoperatively investigate patellofemoral morphology before and after TKR. The approach enables intraoperative measurement of patellofemoral morphologies without radiation exposure. An inherent advantage of intraoperative analysis is the possibility to capture not only the implant design but also the actual implantation of the total knee endoprosthesis components depending on implant positioning and bone resection. In our feasibility study, a sufficient number of included patients could be realized to derive substantial findings [33] and the option to assess the postoperative situation of the trochlear groove [26] compared to the preoperative situation without radiation exposure. To our knowledge, only very few computational intraoperative investigations of patients before and after TKA exist, which highlights the importance of our present study.
In conclusion, the presented method proved to be capable of extracting important morphological parameters of the trochlear groove. Sulcus height and the height of the femoral condyles of the prosthetic trochlea differed from the native trochlea. Future work is needed to enable recruitment of a larger patient cohort and to include different implant designs, and clinical assessment of the correlation between morphological parameters and the postoperative outcome through clinical evaluation scores. This may support the further enhancement of surgical technique and design of femoral components for total knee replacements. Orthopedic surgeons should be aware of the possible changes in trochlear groove geometry. An increase in sulcus height will likely increase patellofemoral pressure and act as a contributor to anterior knee pain.