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Developmental and lethal effects of glyphosate and a glyphosate-based product on Xenopus laevis embryos and tadpoles

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Abstract

Effects of pure glyphosate and a glyphosate-based product were evaluated comparatively using two embryonic development stages of Xenopus laevis as model system. When pure glyphosate was applied in pH adjusted media, lethal or developmental effects were not observed at concentrations up to 500 mg L−1. The 96 h LC50 values for the commercial herbicide, in contrast, were 32.1 and 35.1 mg active ingredient L−1 for embryos and tadpoles, respectively. Since pure glyphosate has no effect on the selected biomarkers, it is thought that developmental toxic effects caused by glyphosate-based products are increased mainly due to formulation additives.

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  1. Laboratory of Environmental Toxicology, Department of Biology, Faculty of Arts and Sciences, Inonu University, 44280, Malatya, Turkey

    Duygu Özhan Turhan, Abbas Güngördü & Murat Ozmen

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  1. Duygu Özhan Turhan
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  2. Abbas Güngördü
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  3. Murat Ozmen
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Correspondence to Abbas Güngördü.

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Turhan, D.Ö., Güngördü, A. & Ozmen, M. Developmental and lethal effects of glyphosate and a glyphosate-based product on Xenopus laevis embryos and tadpoles. Bull Environ Contam Toxicol 104, 173–179 (2020). https://doi.org/10.1007/s00128-019-02774-z

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