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Injektionslipolyse

Injection lipolysis

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Zusammenfassung

Seit 2004 wird weltweit zu einer neuen Therapievariante des medizinisch-ästhetischen Spektrums geforscht: der sog. Injektionslipolyse (IL). Fortschritte im Wissen zu Wirksamkeit und den Wirkmechanismus betreffend gab es v. a. in Deutschland, weil hier im internationalen Vergleich die meisten Anwender zu finden sind. Hintergrund ist, dass in Deutschland für die Wirkstoffkombination Phosphatidylcholin und Desoxycholsäure (PPC-DOC) die Zulassung eines Medikamentes für die i.v.-Anwendung zur Behandlung von Fettembolien besteht. Es ist somit leicht verfügbar, trotzdem ist die subkutane Injektion des Medikaments „Lipostabil N®“ als sog. „off-label use“ einzuordnen. Mittlerweile hat sich die Injektionslipolyse für viele zu einem festen Baustein im Arsenal der ästhetischen Medizin entwickelt. Insbesondere der internationale Zusammenschluss der anwendenden Ärzte in dem sog. Netzwerk Lipolyse (weltweit über 2000 Mitglieder) hat die Entwicklung international gültiger Therapiestandards und -protokolle gefördert. Die Injektion von Phosphatidylcholin/Desoxycholsäure in subkutanes Fettgewebe hat die minimal-invasive ästhetische Medizin, bei strenger Indikationsstellung und nach intensiver Schulung der die Methode einsetzenden Mediziner um einen sinnvollen Baustein erweitert.

Abstract

A new treatment variation in the spectrum of aesthetic medicine has been investigated worldwide since 2004: so-called injection lipolysis. Advances in knowledge regarding the efficacy and mechanism of action have been achieved especially in Germany because most users are found in Germany when compared on an international level. The reason for this is that the combination of phosphatidylcholine and deoxycholic acid as active substances has been approved for i.v. treatment of fat embolisms. It is thus readily available, but the subcutaneous injection of the drug Lipostabil N® is considered as off-label use. Meanwhile injection lipolysis has become an integral component for many in the practice of aesthetic medicine. The international association of physicians performing lipolysis in the so-called NETWORK-Lipolysis (with more than 2,000 members worldwide) has in particular called for the development of internationally recognized treatment standards and protocols. When the indication for its use adheres to strict criteria and the physicians applying the method have participated in intensive training, subcutaneous injection of phosphatidylcholine/deoxycholic acid represents a meaningful addition to the scope of minimally invasive aesthetic medicine.

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  1. Klinik für Dermatologie und Allergologie der Ruhr-Universität Bochum, Gudrunstr. 56, 44791, Bochum, Deutschland

    K. Hoffmann

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Hoffmann, K. Injektionslipolyse. Hautarzt 61, 847–855 (2010). https://doi.org/10.1007/s00105-010-1984-x

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