Zusammenfassung
Das optimale perioperative Flüssigkeitsmanagement wird kontrovers diskutiert. Neben der häufig vorkommenden perioperativen Hypovolämie trägt auch die Hypervolämie entscheidend zur perioperativen Morbidität und Letalität bei, besonders im Hinblick auf verschiedene Krankheitsbilder, präexistente kardiale und pulmonale Funktionseinschränkungen und den operativen Eingriff an sich. Die Konzepte der prä, intra- und postoperativen Flüssigkeitsgabe sind weder ausreichend validiert, noch genügend in ein perioperatives Konzept integriert. Derzeit gelten moderate Flüssigkeitsgaben zur Verbesserung des prä- und postoperativen Wohlbefindens bei klein- bis mittelgroßen chirurgischen Eingriffen als gesichert. Hochrisikopatienten profitieren durch eine zeitgerechte und/oder zielgerichtete Flüssigkeitsgabe unter erweitertem Monitoring. Dem postoperativen Flüssigkeitsmanagement wurde bis dato nicht genügend Aufmerksamkeit geschenkt, aber es scheint durch die Konzepte der „Fast-track-Chirurgie“ neue Anregungen zu bekommen.
Abstract
Optimal perioperative fluid management is still controversial. Besides well known perioperative hypovolaemia, hypervolaemia has an influence on perioperative morbidity and mortality, particularly with regard to the patient’s medical history, a reduced cardiac and pulmonal function and the operation itself. The concepts of preoperative, intraoperative and postoperative fluid administration are neither adequately validated, nor sufficiently integrated into a perioperative concept. At the present, moderate fluid administration to improve preoperative and postoperative outcome is safe in minor or medium surgical procedures. High-risk surgical patients benefit from a time-oriented or/and goal-oriented monitored fluid therapy. In the past only little attention has been concentrated on postoperative fluid management, but may be stimulated by the new concepts of fast track surgery.
This is a preview of subscription content, access via your institution.
Literatur
Adrogue HJ, Madias NE (2000) Hypernatremia. N Engl J Med 342:1493–1499
Agarwal A, Chari P, Singh H (1989) Fluid deprivation before operation. The effect of a small drink. Anaesthesia 44:632–634
Ali SZ, Taguchi A, Holtmann B et al. (2003) Effect of supplemental pre-operative fluid on postoperative nausea and vomiting. Anaesthesia 58:780–784
Allison SP, Lobo DN (2004) Fluid and electrolytes in the elderly. Curr Opin Clin Nutr Metab Care 7:27–33
Andersson TR, Berner NS, Larsen ML et al. (1987) Plasma heparin cofactor II, protein C and antithrombin in elective surgery. Acta Chir Scand 153:291–296
Apfel CC, Stoecklein K, Lipfert P (2005) PONV: a problem of inhalational anaesthesia? Best Pract Res Clin Anaesthesiol 19:485–500
Arieff AI (1999) Fatal postoperative pulmonary edema: pathogenesis and literature review. Chest 115:1371–1377
Arkilic CF, Taguchi A, Sharma N et al. (2003) Supplemental perioperative fluid administration increases tissue oxygen pressure. Surgery 133:49–55
Baig MK, Wexner SD (2004) Postoperative ileus: a review. Dis Colon Rectum 47:516–526
Balogh Z, McKinley BA, Cocanour CS et al. (2003) Supranormal trauma resuscitation causes more cases of abdominal compartment syndrome. Arch Surg 138:637–642
Bartels H, Stein HJ, Siewert JR (1998) Preoperative risk analysis and postoperative mortality of oesophagectomy for resectable oesophageal cancer. Br J Surg 85:840–844
Basse L, Hjort Jakobsen D, Billesbolle P et al. (2000) A clinical pathway to accelerate recovery after colonic resection. Ann Surg 232:51–57
Basse L, Billesbolle P, Kehlet H (2002) Early recovery after abdominal rectopexy with multimodal rehabilitation. Dis Colon Rectum 45:195–199
Basse L, Thorbol JE, Lossl K et al. (2004) Colonic surgery with accelerated rehabilitation or conventional care. Dis Colon Rectum 47:271–277
Baxter CR, Shires T (1968) Physiological response to crystalloid resuscitation of severe burns. Ann N Y Acad Sci 150:874–894
Bennett J, McDonald T, Lieblich S et al. (1999) Perioperative rehydration in ambulatory anesthesia for dentoalveolar surgery. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 88:279–284
Berthoud MC, Reilly CS (1992) Adverse effects of general anaesthetics. Drug Saf 7:434–459
Berwick DM (1991) Controlling variation in health care: a consultation from Walter Shewhart. Med Care 29:1212–1225
Bisgaard T, Kristiansen VB, Hjortso NC et al. (2004) Randomized clinical trial comparing an oral carbohydrate beverage with placebo before laparoscopic cholecystectomy. Br J Surg 91:151–158
Bismuth H, Castaing D, Garden OJ (1989) Major hepatic resection under total vascular exclusion. Ann Surg 210:13–19
Bokey EL, Chapuis PH, Fung C et al. (1995) Postoperative morbidity and mortality following resection of the colon and rectum for cancer. Dis Colon Rectum 38:480–486
Boldt J (2002) Aktuelle Perspektiven in der Volumenersatztherapie. Uni-Med, Bremen
Boyd AD, Tremblay RE, Spencer FC et al. (1959) Estimation of cardiac output soon after intracardiac surgery with cardiopulmonary bypass. Ann Surg 150:613–626
Boyd O (1999) Peri-operative cardiovascular optimization. Best Pract Res Clin Anaesthesiol 13:267–277
Bradshaw BG, Liu SS, Thirlby RC (1998) Standardized perioperative care protocols and reduced length of stay after colon surgery. J Am Coll Surg 186:501–506
Brandstrup B, Tonnesen H, Beier Holgersen R et al. (2003) Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trial. Ann Surg 238:641–648
Callum KG, Gray AJG, Hoile RW et al. (1999) Extremes of age: the 1999 Report of the National Confidential Enquiry into perioperative deaths. National Confidential Enquiry into Perioperative Deaths. London
Campbell IT, Baxter JN, Tweedie IE et al. (1990) IV fluids during surgery. Br J Anaesth 65:726–729
Carmichael P, Carmichael AR (2003) Acute renal failure in the surgical setting. ANZ J Surg 73:144–153
Cartotto R, Choi J, Gomez M et al. (2003) A prospective study on the implications of a base deficit during fluid resuscitation. J Burn Care Rehabil 24:75–84
Chan ST, Kapadia CR, Johnson AW et al. (1983) Extracellular fluid volume expansion and third space sequestration at the site of small bowel anastomoses. Br J Surg 70:36–39
Chandrashekar MV, Irving M, Wayman J et al. (2003) Immediate extubation and epidural analgesia allow safe management in a high-dependency unit after two-stage oesophagectomy. Results of eight years of experience in a specialized upper gastrointestinal unit in a district general hospital. Br J Anaesth 90:474–479
Claridge JA, Crabtree TD, Pelletier SJ et al. (2000) Persistent occult hypoperfusion is associated with a significant increase in infection rate and mortality in major trauma patients. J Trauma 48:8–14
Clergue F, Auroy Y, Pequignot F et al. (1999) French survey of anesthesia in 1996. Anesthesiology 91:1509–1520
Clowes GH Jr, Guercio LR del (1960) Circulatory response to trauma of surgical operations. Metabolism 9:67–81
Cohendy R, Brougere A, Cuvillon P (2005) Anaesthesia in the older patient. Curr Opin Clin Nutr Metab Care 8:17–21
Conway DH, Mayall R, Abdul Latif MS et al. (2002) Randomised controlled trial investigating the influence of intravenous fluid titration using oesophageal Doppler monitoring during bowel surgery. Anaesthesia 57:845–849
Cook R, Anderson S, Riseborough M et al. (1990) Intravenous fluid load and recovery. A double-blind comparison in gynaecological patients who had day-case laparoscopy. Anaesthesia 45:826–830
Cunningham JD, Fong Y, Shriver C et al. (1994) One hundred consecutive hepatic resections. Blood loss, transfusion, and operative technique. Arch Surg 129:1050–1056
Desborough JP (2000) The stress response to trauma and surgery. Br J Anaesth 85:109–117
Dieterich HJ (2001) Kristalloide versus Kolloide. A never ending story? Anaesthesist 50:432–435
Dohrmann R (1959) Einfluss der Operation auf den Wasser-Elektrolythaushalt. In: Dohrmann R (Hrsg) Einführung in die prä- und postoperative Wasser- und Elektrolyttherapie. Springer, Berlin Göttingen Heidelberg, S 17–20
Drummer C, Heer M, Baisch F et al. (1992) Diuresis and natriuresis following isotonic saline infusion in healthy young volunteers before, during, and after HDT. Acta Physiol Scand Suppl 604:101–111
Eagle KA, Berger PB, Calkins H et al. (2002) ACC/AHA guideline update for perioperative cardiovascular evaluation for noncardiac surgery — Executive summary a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1996 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery). Circulation 105:1257–1267
Elhakim M, Sebiae S el, Kaschef N et al. (1998) Intravenous fluid and postoperative nausea and vomiting after day-case termination of pregnancy. Acta Anaesthesiol Scand 42:216–219
Fasting S, Gisvold SE (2002) Serious intraoperative problems – A five-year review of 83,844 anesthetics. Can J Anaesth 49:545–553
Fisher M (1977) Postoperative intravenous therapy. Anaesth Intensive Care 5:339–346
Foster ME, Laycock JR, Silver IA et al. (1985) Hypovolaemia and healing in colonic anastomoses. Br J Surg 72:831–834
Friedrich JB, Sullivan SR, Engrav LH et al. (2004) Is supra-Baxter resuscitation in burn patients a new phenomenon? Burns 30:464–466
Gan TJ, Soppitt A, Maroof M et al. (2002) Goal-directed intraoperative fluid administration reduces length of hospital stay after major surgery. Anesthesiology 97:820–826
Gilbert SS, Easy WR, Fitch WW (1995) The effect of pre-operative oral fluids on morbidity following anaesthesia for minor surgery. Anaesthesia 50:79–81
Gluck SL (1998) Acid-base. Lancet 352:474–479
Goodwin AP, Rowe WL, Ogg TW et al. (1991) Oral fluids prior to day surgery. The effect of shortening the pre-operative fluid fast on postoperative morbidity. Anaesthesia 46:1066–1068
Grocott MP, Mythen MG, Gan TJ (2005) Perioperative fluid management and clinical outcomes in adults. Anesth Analg 100:1093–1106
Gross CR, Lindquist RD, Woolley AC et al. (1992) Clinical indicators of dehydration severity in elderly patients. J Emerg Med 10:267–274
Grube C, Schaper N, Graf BM (2002) Man at risk. Aktuelle Strategien zum Risikomanagement in der Anästhesie. Anaesthesist 51:239–247
Hahn RG (1990) Fluid and electrolyte dynamics during development of the TURP syndrome. Br J Urol 66:79–84
Hamilton-Davies C, Mythen MG, Salmon JB et al. (1997) Comparison of commonly used clinical indicators of hypovolaemia with gastrointestinal tonometry. Intensive Care Med 23:276–281
Harman D (2001) Aging: overview. Ann N Y Acad Sci 928:1–21
Hartl WH, Rittler P (2002) Perioperative Infusionstherapie. Prinzipien. Chirurg 73:1067–1086
Hausel J, Nygren J, Lagerkranser M et al. (2001) A carbohydrate-rich drink reduces preoperative discomfort in elective surgery patients. Anesth Analg 93:1344–1350
Heyland DK, Cook DJ, King D et al. (1996) Maximizing oxygen delivery in critically ill patients: a methodologic appraisal of the evidence. Crit Care Med 24:517–524
Hillebrecht A, Schulz H, Meyer M et al. (1992) Pulmonary responses to lower body negative pressure and fluid loading during head-down tilt bedrest. Acta Physiol Scand Suppl 604:35–42
Holte K, Kehlet H (2002) Compensatory fluid administration for preoperative dehydration – Does it improve outcome? Acta Anaesthesiol Scand 46:1089–1093
Holte K, Sharrock NE, Kehlet H (2002) Pathophysiology and clinical implications of perioperative fluid excess. Br J Anaesth 89:622–632
Holte K, Jensen P, Kehlet H (2003) Physiologic effects of intravenous fluid administration in healthy volunteers. Anesth Analg 96:1504–1509, table of contents
Holte K, Klarskov B, Christensen DS et al. (2004) Liberal versus restrictive fluid administration to improve recovery after laparoscopic cholecystectomy: a randomized, double-blind study. Ann Surg 240:892–899
Hutchinson A, Maltby JR, Reid CR (1988) Gastric fluid volume and pH in elective inpatients. Part I: coffee or orange juice versus overnight fast. Can J Anaesth 35:12–15
Janetzko K, Kluter H, Kirchner H et al. (2001) The effect of moderate hypovolaemia on microcirculation in healthy older blood donors. Anaesthesia 56:103–107
Jeng JC, Jablonski K, Bridgeman A et al. (2002) Serum lactate, not base deficit, rapidly predicts survival after major burns. Burns 28:161–166
Keane PW, Murray PF (1986) Intravenous fluids in minor surgery. Their effect on recovery from anaesthesia. Anaesthesia 41:635–637
Kehlet H (1997) Multimodal approach to control postoperative pathophysiology and rehabilitation. Br J Anaesth 78:606–617
Kern JW, Shoemaker WC (2002) Meta-analysis of hemodynamic optimization in high-risk patients. Crit Care Med 30:1686–1692
Kirby RR (1999) Perioperative fluid therapy and postoperative pulmonary edema: cause-effect relationship? Chest 115:1224–1226
Kita T, Mammoto T, Kishi Y (2002) Fluid management and postoperative respiratory disturbances in patients with transthoracic esophagectomy for carcinoma. J Clin Anesth 14:252–256
Lawlor PG (2002) Delirium and dehydration: some fluid for thought? Support Care Cancer 10:445–454
Leriche R (1934) La maladie postopératoire. Gaz Hopit 107:551
Licker M, Perrot M de, Spiliopoulos A et al. (2003) Risk factors for acute lung injury after thoracic surgery for lung cancer. Anesth Analg 97:1558–1565
Lobo DN (2004) Fluid, electrolytes and nutrition: physiological and clinical aspects. Proc Nutr Soc 63:453–466
Lobo DN (2004) Fluid and electrolytes in the clinical setting. Nestle Nutr Workshop Ser Clin Perform Programme 2004:187–198
Lobo DN, Dube MG, Neal KR et al. (2001) Problems with solutions: drowning in the brine of an inadequate knowledge base. Clin Nutr 20:125–130
Lobo DN, Bostock KA, Neal KR et al. (2002) Effect of salt and water balance on recovery of gastrointestinal function after elective colonic resection: a randomised controlled trial. Lancet 359:1812–1818
Lobo DN, Dube MG, Neal KR et al. (2002) Peri-operative fluid and electrolyte management: a survey of consultant surgeons in the UK. Ann R Coll Surg Engl 84:156–160
Lowell JA, Schifferdecker C, Driscoll DF et al. (1990) Postoperative fluid overload: not a benign problem. Crit Care Med 18:728–733
Macafee DA, Allison SP, Lobo DN (2005) Some interactions between gastrointestinal function and fluid and electrolyte homeostasis. Curr Opin Clin Nutr Metab Care 8:197–203
Maharaj CH, Kallam SR, Malik A et al. (2005) Preoperative intravenous fluid therapy decreases postoperative nausea and pain in high risk patients. Anesth Analg 100:675–682, table of contents
Maltby JR, Sutherland AD, Sale JP et al. (1986) Preoperative oral fluids: is a five-hour fast justified prior to elective surgery? Anesth Analg 65:1112–1116
Maltby JR, Reid CR, Hutchinson A (1988) Gastric fluid volume and pH in elective inpatients. Part II: Coffee or orange juice with ranitidine. Can J Anaesth 35:16–19
McDonald GA, Dubose TD Jr (1993) Hyponatremia in the cancer patient. Oncology (Huntingt) 7:55–64
Mecray PM, Barden RP, Ravdin IS (1990) Nutritional edema: its effect on the gastric emptying time before and after gastric operations. 1937. Nutrition 6:278–289
Meiser A, Casagranda O, Skipka G et al. (2001) Quantifizierung von Blutverlusten. Wie genau ist visuelles Schätzen und wovon hängt die Genauigkeit ab? Anaesthesist 50:13–20
Melendez JA, Barrera R (1998) Predictive respiratory complication quotient predicts pulmonary complications in thoracic surgical patients. Ann Thorac Surg 66:220–224
Melendez JA, Arslan V, Fischer ME et al. (1998) Perioperative outcomes of major hepatic resections under low central venous pressure anesthesia: blood loss, blood transfusion, and the risk of postoperative renal dysfunction. J Am Coll Surg 187:620–625
Miller RD (2004) Anesthesia. Intravascular fluid and electrolyte physiology. In: Miller RD (2004) Miller’s anesthesia. Elsevier Churchill Livingstone. New York, pp 1763–1799
Mittelstaedt H, Kerger H (2004) Perioperatives Management bei elektiven Leberresektionen. Anaesthesiol Intensivmed 45:403–413
Moore FD (1959) Metabolic care of the surgical patient. Saunders, Philadelphia
Muller JM, Erasmi H, Stelzner M et al. (1990) Surgical therapy of oesophageal carcinoma. Br J Surg 77:845–857
Mythen MG, Webb AR (1995) Perioperative plasma volume expansion reduces the incidence of gut mucosal hypoperfusion during cardiac surgery. Arch Surg 130:423–429
Nahtomi-Shick O, Kostuik JP, Winters BD et al. (2001) Does intraoperative fluid management in spine surgery predict intensive care unit length of stay? J Clin Anesth 13:208–212
Nisanevich V, Felsenstein I, Almogy G et al. (2005) Effect of intraoperative fluid management on outcome after intraabdominal surgery. Anesthesiology 103:25–32
Oh MS, Kim HJ (2002) Basic rules of parenteral fluid therapy. Nephron 92 [Suppl 1]:56–59
Parquin F, Marchal M, Mehiri S et al. (1996) Post-pneumonectomy pulmonary edema: analysis and risk factors. Eur J Cardiothorac Surg 10:929–932
Pearson SD, Goulart Fisher D, Lee TH (1995) Critical pathways as a strategy for improving care: problems and potential. Ann Intern Med 123:941–948
Perko MJ, Jarnvig IL, Hojgaard-Rasmussen N et al. (2001) Electric impedance for evaluation of body fluid balance in cardiac surgical patients. J Cardiothorac Vasc Anesth 15:44–48
Phillips PA, Bretherton M, Risvanis J et al. (1993) Effects of drinking on thirst and vasopressin in dehydrated elderly men. Am J Physiol 264:R877–881
Phillips S, Hutchinson S, Davidson T (1993) Preoperative drinking does not affect gastric contents. Br J Anaesth 70:6–9
Pickleman J, Watson W, Cunningham J et al. (1999) The failed gastrointestinal anastomosis: an inevitable catastrophe? J Am Coll Surg 188:473–482
Polanczyk CA, Rohde LE, Goldman L et al. (2001) Right heart catheterization and cardiac complications in patients undergoing noncardiac surgery: an observational study. JAMA 286:309–314
Price JD, Sear JW, Venn RM (2005) Perioperative fluid volume optimization following proximal femoral fracture. Cochrane Database Syst Rev Cd003004
Prien T, Backhaus N, Pelster F et al. (1990) Effect of intraoperative fluid administration and colloid osmotic pressure on the formation of intestinal edema during gastrointestinal surgery. J Clin Anesth 2:317–323
Read MS, Vaughan RS (1991) Allowing pre-operative patients to drink: effects on patients‘ safety and comfort of unlimited oral water until 2 hours before anaesthesia. Acta Anaesthesiol Scand 35:591–595
Rivers EP, Nguyen HB, Huang DT et al. (2004) Early goal-directed therapy. Crit Care Med 32:314–315
Ruchardt A, Lydtin H (1999) Storungen des Natrium- und Wasserhaushaltes. Diagnostik und Therapie. Internist (Berl) 40:W861–871
Rusy BF, Komai H (1987) Anesthetic depression of myocardial contractility: a review of possible mechanisms. Anesthesiology 67:745–766
Sanders G, Mercer SJ, Saeb Parsey K et al. (2001) Randomized clinical trial of intravenous fluid replacement during bowel preparation for surgery. Br J Surg 88:1363–1365
Sandham JD, Hull RD, Brant RF et al. (2003) A randomized, controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients. N Engl J Med 348:5–14
Scheidegger A, Lundsgaard Hansen P, Kupfer K et al. (1979) Hypoproteinämie als Ursache eines postoperativen „interstitiellen“ paralytischen Ileus. Chirurg 50:16–20
Schultz RJ, Whitfield GF, LaMura JJ et al. (1985) The role of physiologic monitoring in patients with fractures of the hip. J Trauma 25:309–316
Seinela L, Pehkonen E, Laasanen T et al. (2003) Bowel preparation for colonoscopy in very old patients: a randomized prospective trial comparing oral sodium phosphate and polyethylene glycol electrolyte lavage solution. Scand J Gastroenterol 38:216–220
Shires GT 3rd, Peitzman AB, Albert SA et al. (1983) Response of extravascular lung water to intraoperative fluids. Ann Surg 197:515–519
Shires T, Williams J, Brown F (1961) Acute change in extracellular fluids associated with major surgical procedures. Ann Surg 154:803–810
Shirreffs SM (2000) Markers of hydration status. J Sports Med Phys Fitness 40:80–84
Shoemaker WC, Appel PL, Kram HB et al. (1988) Prospective trial of supranormal values of survivors as therapeutic goals in high-risk surgical patients. Chest 94:1176–1186
Shoemaker WC, Appel PL, Kram HB (1993) Hemodynamic and oxygen transport responses in survivors and nonsurvivors of high-risk surgery. Crit Care Med 21:977–990
Sinclair S, James S, Singer M (1997) Intraoperative intravascular volume optimisation and length of hospital stay after repair of proximal femoral fracture: randomised controlled trial. BMJ 315:909–912
Slinger PD (1995) Perioperative fluid management for thoracic surgery: the puzzle of postpneumonectomy pulmonary edema. J Cardiothorac Vasc Anesth 9:442–451
Spencer EM (1988) Intravenous fluids in minor gynaecological surgery. Their effect on postoperative morbidity. Anaesthesia 43:1050–1051
Spies CD, Breuer JP, Gust R et al. (2003) Präoperative Nahrungskarenz. Ein Update. Anaesthesist 52:1039–1045
Splinter WM, Schaefer JD (1991) Ingestion of clear fluids is safe for adolescents up to 3 h before anaesthesia. Br J Anaesth 66:48–52
Stephens R, Mythen M (2003) Optimizing intraoperative fluid therapy. Curr Opin Anaesthesiol 16:385–392
Stone JG, Hoar PF, Khambatta HJ (1983) Influence of volume loading on intraoperative hemodynamics and perioperative fluid retention in patients with valvular regurgitation undergoing prosthetic replacement. Am J Cardiol 52:530–533
Stoneham MD, Hill EL (1997) Variability in post-operative fluid and electrolyte prescription. Br J Clin Pract 51:82–84
Sun X, Iles M, Weissman C (1993) Physiologic variables and fluid resuscitation in the postoperative intensive care unit patient. Crit Care Med 21:555–561
Takala J, Meier Hellmann A, Eddleston J et al. (2000) Effect of dopexamine on outcome after major abdominal surgery: a prospective, randomized, controlled multicenter study. European Multicenter Study Group on Dopexamine in Major Abdominal Surgery. Crit Care Med 28:3417–3423
Tremblay LN, Feliciano DV, Rozycki GS (2002) Assessment of initial base deficit as a predictor of outcome: mechanism of injury does make a difference. Am Surg 68:689–693
Turnage WS, Lunn JJ (1993) Postpneumonectomy pulmonary edema. A retrospective analysis of associated variables. Chest 103:1646–1650
Venn R, Steele A, Richardson P et al. (2002) Randomized controlled trial to investigate influence of the fluid challenge on duration of hospital stay and perioperative morbidity in patients with hip fractures. Br J Anaesth 88:65–71
Verheijen Breemhaar L, Bogaard JM, Berg B van den et al. (1988) Postpneumonectomy pulmonary oedema. Thorax 43:323–326
Voelckel WG, Goedecke A von, Fries D et al. (2004) Die Behandlung des hämorrhagischen Schocks. Neue Therapieoptionen. Anaesthesist 53:1151–1167
Wakeling HG, McFall MR, Jenkins CS et al. (2005) Intraoperative oesophageal Doppler guided fluid management shortens postoperative hospital stay after major bowel surgery. Br J Anaesth 95:634–642
Walsh SR, Walsh CJ (2005) Intravenous fluid-associated morbidity in postoperative patients. Ann R Coll Surg Engl 87:126–130
Wiebalck A, Moellhoff T, Hachenberg T et al. (2002) Perioperative Optimierung des Sauerstoffangebotes bei Hochrisikopatienten. Anaesthesiol Intensivmed 43:327–339
Wilkinson AW, Billing BH, Nagy G et al. (1950) Excretion of potassium after partial gastrectomy. Lancet 2:135–137
Williams EL, Hildebrand KL, McCormick SA et al. (1999) The effect of intravenous lactated Ringer’s solution versus 0.9% sodium chloride solution on serum osmolality in human volunteers. Anesth Analg 88:999–1003
Wilson J, Woods I, Fawcett J et al. (1999) Reducing the risk of major elective surgery: randomised controlled trial of preoperative optimisation of oxygen delivery. BMJ 318:1099–1103
Woods MS, Kelley H (1993) Oncotic pressure, albumin and ileus: the effect of albumin replacement on postoperative ileus. Am Surg 59:758–763
Yogendran S, Asokumar B, Cheng DC et al. (1995) A prospective randomized double-blinded study of the effect of intravenous fluid therapy on adverse outcomes on outpatient surgery. Anesth Analg 80:682–686
Zink W, Graf BM (2003) Toxikologie der Lokalanästhetika. Pathomechanismen – Klinik – Therapie. Anaesthesist 52:1102–1123
Interessenkonflikt:
Es besteht kein Interessenkonflikt. Der korrespondierende Autor versichert, dass keine Verbindungen mit einer Firma, deren Produkt in dem Artikel genannt ist, oder einer Firma, die ein Konkurrenzprodukt vertreibt, bestehen. Die Präsentation des Themas ist unabhängig und die Darstellung der Inhalte produktneutral.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Zausig, Y.A., Weigand, M.A. & Graf, B.M. Perioperatives Flüssigkeitsmanagement. Anaesthesist 55, 371–390 (2006). https://doi.org/10.1007/s00101-006-0988-5
Issue Date:
DOI: https://doi.org/10.1007/s00101-006-0988-5
Schlüsselwörter
- Perioperatives Flüssigkeitsmanagement
- Hypovolämie
- Hypervolämie
- Morbidität
- Letalität
Keywords
- Perioperative fluid management
- Hypovolaemia
- Hypervolaemia
- Morbidity
- Mortality