Abstract
Purpose
The accurate volumetric calculation of moving targets/organs is required to use cone-beam computed tomography (CBCT) for replanning purposes. This study was aimed to correct the reconstructed volume losses of moving phantoms by phase-specific CBCT.
Materials and methods
Planning fan-beam CT (FBCT) of five hepatobiliary/gastrointestinal/pancreatic cancer patients were acquired under active breathing control and compared with free-breathing CBCT for kidney volumes. Three different-sized ball phantoms were scanned by FBCT and CBCT. Images were imported to a planning system to compare the reconstructed volumes. The phantoms were moved longitudinally on an oscillator with different amplitudes/frequencies. The phase-specific projections of CBCT for moving phantoms were selected for volume reconstruction.
Results
The differences in reconstructed volumes of static small, medium, large phantoms between FBCT and CBCT were − 6.7%, − 2.3%, and − 2.0%, respectively. With amplitudes of 7.5–20 mm and frequencies of 8–16 oscillations/min, volume losses on CBCT were comparable with FBCT in large moving phantoms (range 9.1–27.2%). Amplitudes were more subject to volume losses than frequencies. On phase-specific CBCT, volume losses were reduced to 2.3–6.5% by reconstruction using 2–3 projections at end/midoscillation phase.
Conclusion
Amplitude had more impact than frequency on volume losses of moving phantoms on CBCT. Phase-specific CBCT reduced volume losses.
Zusammenfassung
Ziel
Die genaue volumetrische Berechnung sich bewegender Ziele/Organe ist für die Verwendung einer Kegelstrahl-Computertomographie („cone beam“, CBCT) für Neuplanungszwecke erforderlich. Diese Studie hatte zum Ziel, den rekonstruierten Volumenverlust eines Bewegungsphantoms durch eine phasenspezifische CBCT zu korrigieren.
Material und Methodik
Eine Planungsfächerstrahl-CT („fan-beam“, FBCT) von 5 Hepatobiliär-/Gastrointestinal-/Pankreaskarzinompatienten wurde unter aktiver Atemkontrolle ausgeführt und jeweils mit einer CBCT unter freier Atmung hinsichtlich des Nierenvolumens verglichen. Drei Kugelphantome unterschiedlicher Größe wurden durch FBCT und CBCT gescannt. Die Bilder wurden in ein Planungssystem importiert und mit den rekonstruierten Volumen verglichen. Die Phantome waren longitudinal um einen Oszillator mit unterschiedlichen Amplituden/Frequenzen verschoben. Die Phasen-spezifischen Projektionen der CBCT für Bewegungsphantome wurden zur Volumenrekonstruktion ausgewählt.
Ergebnisse
Die Unterschiede rekonstruierter Volumen von statischen kleinen, mittleren und großen Phantomen zwischen FBCT und CBCT waren jeweils − 6,7%, − 2,3% und − 2,0%. Mit Amplituden von 7,5–20 mm und Frequenzen von 8–16 Oszillationen/Minute kam es in großen Bewegungsphantomen (Bandbreite: 9,1–27,2%) zu Volumenverlusten bei der CBCT im Vergleich mit der FBCT. Amplitudenveränderungen trugen eher zu Volumenverlusten bei als zu Veränderungen der Frequenzen. Bei Phasen-spezifischer CBCT wurden die Volumenverluste durch Rekonstruktion auf 2,3–6,5% reduziert, indem 2–3 Projektionen in der End-/Mittel-Oszillationsphase verwendet wurden.
Schlussfolgerung
Auf die Volumenverluste von Bewegungsphantomen hat die Amplitude bei der CBCT größeren Einfluss als die Frequenz. Eine Phasen-spezifische CBCT reduziert die Volumenverluste.
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Acknowledgments
This work was supported by National Science Council, Execute Yuan, Taiwan, ROC (NSC 99-2628-B-002-071-MY3, 99-2627-B-002-008), and National Taiwan University Hospital grants NTUH 99S1361, 99N1425, 100S1552.
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The corresponding author states that there are no conflicts of interest.
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Chao, HL., Chen, WL., Hu, CC. et al. Phase-specific cone beam computed tomography reduces reconstructed volume loss of moving phantom. Strahlenther Onkol 188, 77–83 (2012). https://doi.org/10.1007/s00066-011-0012-0
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DOI: https://doi.org/10.1007/s00066-011-0012-0