Abstract
This paper presents a computational vascular fluid-structure interaction (FSI) methodology and its application to patient-specific aneurysm models of the middle cerebral artery bifurcation. A fully coupled fluid-structural simulation approach is reviewed, and main aspects of mesh generation in support of patient-specific vascular FSI analyses are presented. Quantities of hemodynamic interest such as wall shear stress and wall tension are studied to examine the relevance of FSI modeling as compared to the rigid arterial wall assumption. We demonstrate the importance of including the flexible wall modeling in vascular blood flow simulations by performing a comparison study that involves four patient-specific models of cerebral aneurysms varying in shape and size.
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Acknowledgments
We wish to thank the Texas Advanced Computing Center (TACC) at the University of Texas at Austin for providing HPC resources that have contributed to the research results reported within this paper. This work was partially supported by a research grant from the regional health authorities in northern Norway. Support of Teragrid Grant No. MCAD7S032 is also gratefully acknowledged. We thank Prof. Tor Ingebrigtsen, Institute for Clinical Medicine, University of Tromsø,Norway and theDepartment ofNeurosurgery, theUniversity Hospital of North Norway, for his clinical expertise to improve medical reality of the presented simulations.
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Open Access This is an open access article distributed under the terms of the Creative Commons Attribution Noncommercial License (https://creativecommons.org/licenses/by-nc/2.0), which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
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Bazilevs, Y., Hsu, MC., Zhang, Y. et al. A fully-coupled fluid-structure interaction simulation of cerebral aneurysms. Comput Mech 46, 3–16 (2010). https://doi.org/10.1007/s00466-009-0421-4
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DOI: https://doi.org/10.1007/s00466-009-0421-4