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Fluid–structure Interaction Modeling of Aneurysmal Conditions with High and Normal Blood Pressures

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Abstract

Hemodynamic factors like the wall shear stress play an important role in cardiovascular diseases. To investigate the influence of hemodynamic factors in blood vessels, the authors have developed a numerical fluid–structure interaction (FSI) analysis technique. The objective is to use numerical simulation as an effective tool to predict phenomena in a living human body. We applied the technique to a patient-specific arterial model, and with that we showed the effect of wall deformation on the WSS distribution. In this paper, we compute the interaction between the blood flow and the arterial wall for a patient-specific cerebral aneurysm with various hemodynamic conditions, such as hypertension. We particularly focus on the effects of hypertensive blood pressure on the interaction and the WSS, because hypertension is reported to be a risk factor in rupture of aneurysms. We also aim to show the possibility of FSI computations with hemodynamic conditions representing those risk factors in cardiovascular disease. The simulations show that the transient behavior of the interaction under hypertensive blood pressure is significantly different from the interaction under normal blood pressure. The transient behavior of the blood-flow velocity, and the resulting WSS and the mechanical stress in the aneurysmal wall, are significantly affected by hypertension. The results imply that hypertension affects the growth of an aneurysm and the damage in arterial tissues.

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Authors and Affiliations

  1. Department of Chemical Engineering, Imperial College, South Kensington Campus, London, SW7 2AZ, UK

    Ryo Torii

  2. Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba, Meguro, Tokyo, 153-8505, Japan

    Marie Oshima

  3. Japan Automobile Research Institute, 2530 Karima, Tsukuba, Ibaraki, 305-0822, Japan

    Toshio Kobayashi

  4. Department of Neurosurgery, Ogura Hospital, 4-2-5 Nakamachi, Setagaya, Tokyo, 158-8585, Japan

    Kiyoshi Takagi

  5. Mechanical Engineering, Rice University—MS 321, 6100 Main Street, Houston, TX, 77005, USA

    Tayfun E. Tezduyar

Authors
  1. Ryo Torii
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  2. Marie Oshima
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  3. Toshio Kobayashi
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  4. Kiyoshi Takagi
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  5. Tayfun E. Tezduyar
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Correspondence to Ryo Torii.

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Torii, R., Oshima, M., Kobayashi, T. et al. Fluid–structure Interaction Modeling of Aneurysmal Conditions with High and Normal Blood Pressures. Comput Mech 38, 482–490 (2006). https://doi.org/10.1007/s00466-006-0065-6

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  • DOI: https://doi.org/10.1007/s00466-006-0065-6

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