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Studies on the gastric hunger mechanism

  • Clinical Medicine: Diseases Of Digestion
  • Published:
The American Journal of Digestive Diseases

Conclusions

1. Hunger contractions are not directly related to the blood sugar level.

2. Gastric motility resulting from food deprivation or from insulin administration can be stopped by placing a dextrose solution in the stomach. Only the activity induced by insulin can be stopped by dextrose intravenously.

3. Insulin is not capable of producing hunger contractions in animals suffering a deficiency of vitamin B.

4. Either a deficiency of vitamin B or the resulting lack of food materials in the digestive tract causes a decreased tolerance for dextrose.

5. There is a dissociation in gastric activity between secretion and motility. Secretion has been observed to decline while motility was increasing.

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Authors and Affiliations

  1. Portland, Oregon

    Ira A. Manville & Eldon G. Chuinard

Authors
  1. Ira A. Manville
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  2. Eldon G. Chuinard
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From the Department of Physiology, University of Oregon Medical School, Portland Oregon.

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Manville, I.A., Chuinard, E.G. Studies on the gastric hunger mechanism. American Journal of Digestive Diseases and Nutrition 1, 688–693 (1934). https://doi.org/10.1007/BF02999573

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  • DOI: https://doi.org/10.1007/BF02999573

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