Conclusion
The analysis presented of modern data about the functioning of calcium channels in cellular membranes shows that we are dealing with an extremely complex and dynamic system for generation of intracellular signals, one which participates in the coupling of all aspects of cellular activity with the primary processes in the plasmalemma. The diversity of calcium channels produces a large variety of such signals, thus reflecting the variability of external influences on the cell. At the same time, because of the unique physicochemical properties of calcium ions, which enable their specific binding to a large class of protein molecules, the calcium signals become the most universal intracellular messengers suitable for triggering other more specific physicochemical and biochemical cellular reactions.
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Kostyuk, P.G. Calcium channels in cellular membranes. J Mol Neurosci 2, 123 (1990). https://doi.org/10.1007/BF02896838
DOI: https://doi.org/10.1007/BF02896838