Summary
A case of meningitis due to an unusual organism,Haemophilus aphrophilus in an adult is described. In spite of rapid clearance of the organism from the cerebrospinal fluid with intravenous cefotaxime, fever persisted over 8 days of therapy and infection was complicated by hydrocephalus.H. aphrophilus meningitis is uncommon and has not been previously reported in an adult male.
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Elster, S. K., Mattes, L. M., Meyers, B. R., Jurado, R. A.:Haemophilus aphrophilus endocarditis: review of 23 cases. Am. J. Cardiol. 35 (1975) 72–79.
Sutter, V. L., Finegold S. M.:Haemophilus aphrophilus infections: clinical and bacteriologic studies. Ann. N. Y. Acad. Sci. 174 (1970) 468–487.
Duel, P., Siboni, K., Jensen, T. G.: Intracranial abscesses in Odense Hospital. Survey of bacteriology, epidemiology, and treatment with antibiotics, 1963–1989. Dan. Med. Bull. 38 (1991) 407–410.
Stephanian, E., Coffey, R. J., Segal, R.: Intervertebral disc space infection and osteomyelitis due toHaemophilus species: report of two cases and review. J. Spinal Disord. 2 (1989) 114–119.
Bejuk, D., Kuzman, I., Soldo, I., Kuzmanovic, N., Popovic-Uroic, T.: Vertebral osteomyelitis caused byHaemophilus aphrophilus. Eur. J. Clin. Microbiol. 12 (1993) 643–644.
Page, M. I., King, E. O.: Infection due toActinobacillus actinomycetemcomitans, andHaemophilus aphrophilus. N. Engl. J. Med. 275 (1966) 181–188.
Bieger, R. C., Brewer, N. S., Washington, II,J. A.:Haemophilus aphrophilus: a microbiologic and clinical review and report of 42 cases. Medicine 57 (1978) 345–355.
Petty, B. G., Burrow, C. R., Robinson, R. A., Bulkley, G. B.:Haemophilus aphrophilus meningitis followed by vertebral osteomyelitis and suppurative psoas abscess. Am. J. Med. 78 (1985) 159–162.
Vandepitte, J., Eyckmans, L., Cosemans, J.: Een geval van meningitis veroorzaakt doorHaemophilus aphrophilus. Ned. Tijdschr. Geneeskd. 113 (1969) 1346.
Wang, K. F., Wu, C. M., Wu, L. J., Tsang, S. C., Chen, H. M., Hong, Y. C.:Haemophilus aphrophilus meningitis: report of one case. Acta Paediatr. Sin. 34 (1993) 412–417.
Kim, C. B., King, M., Dailey, A. K., Sandlin, D.: A case of meningitis withHaemophilus aphrophilus—a case report. Journal of Indiana State Medical Association 67 (1974) 255–257.
Miano, A., Cipolloni, A. P., Casadel, G. P., Petrone, M., Biasini, G. C.: NeonatalHaemophilus aphrophilus meningitis. Helv. Paediatr. Acta 31 (1976) 499–501.
Maggiore, G., Scotta, M. S., DeGiacomo, C., Malfa, S., Azzini, M.: Bacteremia and meningitis associated withHaemophilus aphrophilus infection in a previously healthy child. Infection 10 (1982) 375.
Tempro, P. J., Slots, J.: Selective medium for the isolation ofHaemophilus aphrophilus from the human periodontium and other oral sites and the low proportion of the organism in the oral cavity. J. Clin. Microbiol. 23 (1986) 777–782.
Abla, A. A., Maroon, J. C., Slifkin, M.: Brain abscess due toHaemophilus aphrophilus: possible canine transmission. Neurosurgery 19 (1986) 123–124.
O'Driscoll, J. C., Keene, G. S., Weinbren, M. J., Johnson, A. P., Palepou, M.-F., George, R. C.:Haemophilus aphrophilus discitis and vertebral osteomyelitis. Scand. J. Infect. Dis. 27 (1995) 291–293.
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Adeyemi-Doro, F.A.B., Hui, A.C.F., Ho, F.N.Y. et al. Haemophilus aphrophilus meningitis complicated by hydrocephalus in an immunocompetent adult. Infection 26, 405–407 (1998). https://doi.org/10.1007/BF02770846
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DOI: https://doi.org/10.1007/BF02770846