Abstract
A total of 26 patients with familial polyposis coli without extracolonic manifestations were examined by gastroduodenoscopy. Histologically verified polyps were found in 18 patients (69 percent, 95 percent confidence limits 48–86). Gastric adenoma was diagnosed in one patient, fundic gland polyposis in six patients, and duodenal adenomas in 12 patients. It is concluded that the incidence of gastroduodenal polyps is independent of the clinical presence of other extracolonic manifestations. It is advisable that polyposis patients should be followed with gastroduodenoscopy and biopsy of polyps.
Similar content being viewed by others
References
Ushio K, Sasagawa M, Doi H, et al. Lesions associated with familial polyposis coli: studies of lesions of the stomach, duodenum, bones and teeth. Gastrointest Radiol 1976;1:67–80.
Watanabe H, Enjoji M, Yao T, Ohsato K. Gastric lesions in familial adenomatosis coli: their incidence and histologic analysis. Hum Pathol 1978;9:269–83.
Järvinen H, Nyberg M, Peltokallio P. Upper gastrointestinal tract polyps in familial adenomatosis coli Gut 1983;24:333–9.
Burt RW, Berenson MM, Lee RG, Tolman KG, Freston JW, Gardner EJ. Upper gastrointestinal polyps in Gardner's syndrome. Gastroenterology 1984;86:295–301.
Johansen Aa. Early gastric cancer. Thesis, Copenhagen, Denmark, 1981.
Hauser G. Ueber Polyposis intestinalis adenomatosa und deren Beziehungen zur Krebsentwicklung. Deutsche Arch Klin Med 1895;55:429–48.
Cabot RC. Case records of the Massachusetts General Hospital: Case 21061. N Engl J Med 1935;212:263–7.
Utsunomiya J, Maki T, Iwama T, et al. Gastric lesion of familial polyposis coli. Cancer 1974;34:745–54.
Nishiura M, Hirota T, Itabashi M, Ushio K, Yamada T, Oguro Y. A clinical and histopathological study of gastric polyps in familial polyposis coli. Am J Gastroenterol 1984;79:98–103.
Ohsato K, Yao T, Watanabe H, Iida M, Itoh H. Small-intestinal involvement in familial polyposis diagnosed by operative intestinal fiberscopy: report of four cases. Dis Colon Rectum 1977; 20:414–20.
Iida M, Yao T, Itoh H, Ohsato K, Watanabe H. Endoscopic features of adenoma of the duodenal papilla in familial polyposis of the colon. Gastrointest Endosc 1981;27:6–8.
Järvinen HJ, Nyberg M, Peltokallio P. Biliary involvement in familial adenomatosis coli. Dis Colon Rectum 1983;26:525–8.
Ranzi T, Castagnone D, Velio P, Bianchi P, Polli EE. Gastric and duodenal polyps in familial polyposis coli. Gut 1981;22:363–7.
Sugihara K, Muto T, Kamiya J, Konishi F, Sawada T, Morioka Y. Gardner's syndrome associated with periampullary carcinoma, duodenal and gastric adenomatosis. Dis Colon Rectum 1982;25: 766–71.
Bussey HJR. Extracolonic lesions associated with polyposis coli. Proc R Soc Med 1972;65:294.
Alm T, Licznerski G. The intestinal polyposes Clin Gastroenterol 1973;2:577–602.
Bülow S. The Danish Polyposis Register: description of the methods of detection and evaluation of completeness. Dis Colon Rectum 1984;27:351–5.
Author information
Authors and Affiliations
Additional information
Grants: Dr. Bülow has received grants from The Danish Cancer Society (809/71 and 87/80), “Max og Anna Friedmanns Legat,” “Ferdinand og Ellen Hindsgauls Fond” and “Arkitekt Holger Hjortenberg og hustru, Dagmar Hjortenbergs Fond.”
About this article
Cite this article
Bülow, S., Lauritsen, K.B., Johansen, A. et al. Gastroduodenal polyps in familial polyposis coli. Dis Colon Rectum 28, 90–93 (1985). https://doi.org/10.1007/BF02552651
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02552651