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Familial Adenomatous Polyposis

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Video Capsule Endoscopy

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Abstract

The incidence of small-bowel polyps is very low in the general population, but it is significantly increased in hereditary polyposis syndromes such as familial adenomatous polyposis (FAP). FAP is caused by an autosomal dominant inherited defect in the APC gene, a classical tumor suppressor gene (Figs. 35.1 and 35.2). Colon polyposis is the most striking clinical manifestation, with more than 100 polyps (Fig. 35.3), leading in almost all patients to colorectal carcinoma. Prophylactic colectomy is recommended after adolescence.

The work was first published in 2006 by Springer Medizin Verlag Heidelberg with the following title: Atlas of Video Capsule Endoscopy.

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Author information

Authors and Affiliations

  1. Department of Medicine, Cleveland Clinic Foundation, Cleveland, OH, USA

    Carol Burke

  2. Department of Medicine, Ruhr-University Bochum, Knappschaftskrankenhaus, Bochum, Germany

    Christian P. Pox & Wolff Schmiegel

  3. Department of Internal Medicine, Bethesda Krankenhaus Bergedorf, Hamburg, Germany

    Martin Keuchel

Authors
  1. Carol Burke
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  2. Christian P. Pox
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  3. Wolff Schmiegel
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  4. Martin Keuchel
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Corresponding author

Correspondence to Carol Burke .

Editor information

Editors and Affiliations

  1. Department of Internal Medicine, Bethesda Krankenhaus Bergedorf, Academic Teaching Hospital of the University of Hamburg, Hamburg, Germany

    Martin Keuchel

  2. 1st Medical Department, Asklepios Klinik Altona, Academic Teaching Hospital of the University of Hamburg, Hamburg, Germany

    Friedrich Hagenmüller

  3. Dept. Internal Medicine, Division of Gastroenterology and Hepatology, The Jikei University School of Medicine, Tokyo, Japan

    Hisao Tajiri

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© 2014 Springer-Verlag Berlin Heidelberg

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Burke, C., Pox, C.P., Schmiegel, W., Keuchel, M. (2014). Familial Adenomatous Polyposis. In: Keuchel, M., Hagenmüller, F., Tajiri, H. (eds) Video Capsule Endoscopy. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-44062-9_35

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  • DOI: https://doi.org/10.1007/978-3-662-44062-9_35

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  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-44061-2

  • Online ISBN: 978-3-662-44062-9

  • eBook Packages: MedicineMedicine (R0)

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