Skip to main content
SpringerLink
Log in

A study of the postnatal change in trace element levels in rat tissues by thermal neutron activation analysis

  • Physical Methods Section
  • Published:
Journal of Radioanalytical Chemistry Aims and scope Submit manuscript

Abstract

In order to obtain information about postnatal changes in trace element levels in rat tissues, the age-dependent variations in the concentrations of 6 elements (Fe, Zn, Co, Se, Rb and Cs) were investigated by thermal neutron activation analysis. Several variation patterns were revealed in their concentrations as a function of postnatal age, depending on the combination of an element and an organ: (1) A steady state without significant variations (Zn and Se in brain, Rb and Cs in liver), (2) accumulation till a steady level is attained in time (Se in liver and kidney, Co in kidney), (3) depletion till a steady level is attained in time (Fe and Co in brain, Zn in liver and kidney, Rb and Cs in kidney), (4) permanent depletion (Rb and Cs in brain), and 95) initial drop followed by gradual increase in concentration levels (Fe in liver and kidney, Co in liver)

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. T. SATO, T. KATO J. Radioanal. Chem., 53 (1979) 181.

    Article  CAS  Google Scholar 

  2. T. SATO, T. KATO, Radiochem. Radioanal. Letters, 42 (1980) 227.

    CAS  Google Scholar 

  3. T. MAŽIERE, C. LOC'H, O. STULZAFT, A. GAUDRY, D. COMAR, J. Radioanal. Chem., 37 (1977) 617.

    Article  Google Scholar 

  4. B. BERGMAN, R. SJÖSTRÖM, K. R. WING, Acta Physio.. Scand., 92 (1974) 440.

    Article  CAS  Google Scholar 

  5. R. A. McCANCE, E. M. WIDDOWSON, J. Physiol., 112 (1951) 450.

    CAS  Google Scholar 

  6. D. D. DUNGAN, C. L. KEEN, B. LÖNNERDAL, L. S. HURLEY, Fed. Proc., 39 (1980) 903.

    Google Scholar 

  7. P. C. MANGAL, J. S. SOHAL, Indian J. Exp. Biol., 16 (1978) 685.

    CAS  Google Scholar 

  8. J. J. DOYLE, D. E. CLARK, J. O. NORMAN, Bull. Environm. Contam. Toxicol., 21 (1979) 225.

    Article  CAS  Google Scholar 

  9. B. KOFOD, European J. Pharmacol., 13 (1970) 40.

    Article  CAS  Google Scholar 

  10. A. MAZUR, A. CARLETON, Blood, 26 (1965) 317.

    CAS  Google Scholar 

  11. W. E. KOLLMER, P. SCHRAMEL, Phys. Med. Biol., 17 (1972) 555.

    Article  CAS  Google Scholar 

  12. C. L. KEEN, B. LÖNNERDAL, M. V. SLOAN, L. S. HURLEY, J. Nutr., 110 (1980) 897.

    CAS  Google Scholar 

  13. P. B. MUTCH, L. S. HURLEY, J. Nutr., 104 (1974) 828.

    CAS  Google Scholar 

  14. L. S. HURLEY, J. R. DUNCAN, M. V. SLOAN, C. D. ECKHERT, Proc. Natl. Acad. Sci. USA, 74 (1977) 3547.

    Article  CAS  Google Scholar 

  15. M. SHINOGI, K. FUKUDA, M. NAKAZAWA, I. MORI, Chem. Pharm. Bull., 28 (1980) 2094.

    CAS  Google Scholar 

  16. A. B. R. THOMSON, L. S. VALBERG, D. G. SINCLAIR, J. Clin. Invest., 50 (1971) 2384.

    Article  CAS  Google Scholar 

  17. W. FORTH, W. RUMMEL, Physiol. Rev., 53 (1973) 724.

    CAS  Google Scholar 

  18. G. BECKER, H. HUEBERS, W. RUMMEL, Glut, 38 (1979) 397.

    CAS  Google Scholar 

  19. E. P. NOVIKOVA, Fed. Proc., 23 (1964) T459.

    Google Scholar 

  20. T. HASEGAWA, Jap. J. Hyg., 29 (1974) 289.

    CAS  Google Scholar 

  21. K. SCHWARZ, C. M. FOLTZ, J. Am. Chem. Soc., 79 (1957) 3292.

    Article  CAS  Google Scholar 

  22. J. N. THOMPSON, M. L. SCOTT, J. Nutr., 97 (1969) 335.

    CAS  Google Scholar 

  23. R. T. GROSS, R. BRACCI, N. RUDOLPH, et al., Blood, 29 (1967) 481.

    CAS  Google Scholar 

  24. B. E. GLADNER, M. E. CONRAD, Pediatr. Res., 6 (1972) 900.

    Google Scholar 

  25. Unpublished data.

  26. R. R. FIEVE, H. MELTZER, R. M. TAYLOR, Psychopharmacologia, 20 (1971) 307.

    Article  CAS  Google Scholar 

  27. R. R. FIEVE, H. MELTZER, D. L. DUNNER, M. LEVITT, J. MENDLEWICZ, A. THOMAS, Am. J. Psychiatry, 130 (1973) 55.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Tokyo Metropolitan Institute for Neuroscience, Fuchu, Tokyo, Japan

    T. Sato

Authors
  1. T. Sato
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sato, T. A study of the postnatal change in trace element levels in rat tissues by thermal neutron activation analysis. J. Radioanal. Chem. 76, 215–224 (1983). https://doi.org/10.1007/BF02519671

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02519671

Keywords

Search

Navigation