Abstract
Plasma level of lipid-standardized vitamin E is decreased, while the concentration of inflammatory transmitters C3a(desArg) and C5a(desArg) is elevated in heterozygous familial hypercholesterolemia caused by apoB,E-receptor deficiency. Leukocytes isolated from these patients exhibit enhanced spontaneous aggregation of superoxide anion generation and are resistant to activation with exogenous platelet activation factor (10−6 M).
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 125, No. 2, pp. 213–216, February, 1998
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Chernyad'eva, I.F., Lopata, N.S., Muzya, G.I. et al. Peculiarities of oxidative stress in the plasma of patients with familial hypercholesterolemia. Bull Exp Biol Med 125, 187–189 (1998). https://doi.org/10.1007/BF02496855
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DOI: https://doi.org/10.1007/BF02496855