Abstract
We analyzed the distribution frequency of HLA-A and-B antigens in populations of the major Balkan area in an attempt to study the various hypotheses on the genetic history of populations of the area. Among these hypotheses are these for genetic change between northern and southern populations of Greece (Barbujani and Sokal 1990) and also those for genetic similarities between North Italy and Greece as a result of colonization of Italy by Greeks (“Magna Grecia”) in classical times (Piazza et al 1988). It seems that three main groups are grossly formed within the populations studied, which is in agreement with historical data.
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References
Barbujiani G, Sokal RS (1990) Zones of sharp genetic change in Europe are also linguistic boundaries. Proceedings of the National Academy of Sciences (USA) 87: 1816–1819
Cavalli-Sforza LL, Bodmer W, Dausset J (1997) Support for genetic diversity project. Nature 390: 221
Kondopoulou H, Loftus R, Kouvatsi R, Triantaphyllidis C. (1999) Genetic studies in 5 Greek population samples using 12 highly polymorphic DNA loci. Hum Biol 71: 27–42
Konstantopoulos K. (1984) A comparative study of the distribution frequency of HLA-A and-B antigens in Greeks from the southern and northern parts of the country. PhD Thesis, University of Athens, Athens
Nei M. (1972) Genetic distance between populations. American Naturalist 106: 283–292
Piazza A, Sgaramella-Zonta L, Glucman E, Cavalli-Sforza LL. (1975) The Fifth Histocombatibility Workshop. Gene Frequency data: A phylogenetic analysis. Tissue Antigens 5: 445–463
Piazza N, Cappello E, Olivetti E, Rendine S (1988) A genetic history of Italy. Annals of Human Genetics 52: 302–313
Polymenidis Z: A study of HLA-A and-B antigens in a sample of the Greek population. PhD Thesis, University of Thessaloniki, Thessaloniki 1978
Ryder LP, Andersen E, Svejigaard A. (1978) An HLA map of Europe. Hum Heredity 28: 171–200
Saitou N, Nei M (1987) The neighbour-joining method: A new method for reconstructing phylogenetic trees. Molecular Biology and Evolution 4: 406–425
Theocharis S, Konstantopoulos K, Bannis K, Zervas J (1977) HLA-A and-B antigens and larynx carcinoma in Greeks. Ups J Med Sci 102: 133–136
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Konstantopoulos, K., Sourdis, J. The distribution of HLA-A and-B antigens among populations in the major Balkan area. Int. J. Anthropol. 16, 245–248 (2001). https://doi.org/10.1007/BF02447233
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DOI: https://doi.org/10.1007/BF02447233