Abstract
It is shown that the effect of amino-acid preparations (levamine-70–70, cerebrolysin, and aviamine) is dose-dependent. Thus, levamine-70 and cerebrolysin at 65 mg/kg do not affect the immune response but stimulate phagocytosis. Aviamine at 65 mg/kg inhibits the immune response but stimulates phagocytosis and in a dose of 6.5×10−2 mg/kg boosts both processes.
Similar content being viewed by others
References
G. A. Belokrylov and I. V. Molchanova,Byull. Eksp. Biol. Med.,113, No 2, 165–166 (1992).
G. A. Belokrylov, I. V. Molchanova, and O. Ya. Popova,,108, No 11, 584–587 (1989).
L. S. Kolabskaya, in:The Methods of Production, Physical and Chemical Characteristics of Avian Blood Preparations, and Their Use in Commercial Poultry Farming. Dissertation [in Russian], Moscow (1987).
G. A. Belokrylov, O. Ya. Popova, I. V. Molchanova,et al., Int. J. Immunopharmacol. 14, No 7, 1285–1292 (1992).
N. K. Jerne and A. A. Nordin,Science,140, 405 (1963).
Author information
Authors and Affiliations
Additional information
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, No 5, pp. 500–501, May, 1994
Rights and permissions
About this article
Cite this article
Belokrylov, G.A., Popova, O.Y., Derevnina, O.N. et al. Ambiguity of the effect of high and low doses of amino-acid preparations on the immune response and phagocytosis in mice. Bull Exp Biol Med 117, 497–499 (1994). https://doi.org/10.1007/BF02444299
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02444299