Abstract
A trimethoxy derivative with three nonequivalent methoxy groups was obtained from 2,2′, 4-trichloro-6′-phenyl-4′ 5-dipyrimidinyl. Rearrangement of 2,2′, 4-trimethoxy-6′-phenyl-4′, 5-dipyrimidinyl under Hubert-Johnson conditions and thermal rearrangement with and without a catalyst make it possible to obtain 2′,4-dimethoxy-1-methyl-2-oxo-and 2′-methoxy-1,3-dimethy1-2,4-dioxodipyrimidinyls and both tri-N-methyl isomers, viz., the 1,1′, 3-and 1,3,3′-trimethyl derivatives. The possibility of obtaining N-methyl derivatives of trioxodipyrimidinyl by methylation under various conditions was also examined.
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See [1] for communication 70.
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 398–403, March, 1980.
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Naumenko, I.I., Mikhaleva, M.A. & Mamaev, V.P. Pyrimidines. 71. Rearrangements of 2,2′,4-trimethoxy-6′-phenyl-4′,5-dipyrimidinyl to n-methyl oxo derivatives. Chem Heterocycl Compd 16, 303–308 (1980). https://doi.org/10.1007/BF02401733
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DOI: https://doi.org/10.1007/BF02401733