Summary
Proteins secreted by the rat submandibular gland after administration of autonomic agonists have been fractionated by sodium dodecyl sulphate (SDS) — polyacrylamide gel electrophoresis. α-adrenoceptor, β-adrenoceptor and muscarinic agonists were all found to cause the secretion of different protein populations.
Similar content being viewed by others
Literatur
N. Emmelin, J. Holmberg and P. Ohlin, Br. J. Pharmac.25, 134 (1965).
Y. Yoshida, R.L. Sprecher, C.A. Schneyer and L.H. Scheyer, Proc. Soc. exp. Biol. Med., N.Y.126, 912 (1967).
J.A. Young and C.J. Martin, Pflügers Arch.327, 285 (1971).
J.R. Martinez, D.O. Quissell, D.L. Wood and M. Giles, J. Pharmac. exp. Ther.194, 384 (1975).
J.A. Young, D.I. Cook, G. Jones, J. McGirr and C. Thompson, Aust. J. exp. Biol. med. Sci.57, 555 (1979).
D.O. Quissell, Am. J. Physiol.238, C90 (1980).
D.O. Quissell and K.A. Barzen, Am. J. Physiol.238, C99 (1980).
O.H. Peterson and G.L. Pederson, J. Membrane Biol.16, 353 (1974).
O.H. Peterson Physiol. Rev.56, 535 (1976).
J.A. Young and E.W. van Lennep, in: ‘Membrane transport in biology’, vol. 4, p. 563. Ed. G. Giebisch. Springer, Berlin, Heidelberg, New York 1979.
A. Thomas, Ph.D. Thesis, Univ. of Glasgow, Glasgow 1978.
K. Weber and M. Osborn, J. biol. Chem.244, 4406 (1969).
A.L. Shapiro, E. Vinuela and J.V. Maizel, Biochem. biophys. Res. Commun.28, 815 (1967).
R.W. Matthews, Archs oral. Biol.19, 989 (1974).
N. Weiner, in: ‘The Pharmacological Basis of Therapeutics’, 6th edn, p. 138. Eds A. Goodman Gilman, L.S. Goodman and A. Gilman. Macmillan Publishing Co., New York 1980.
K. Abe, K. Yonenda, R. Fujita, Y. Yokota and C. Dawes, J. dent. Res.59, 1627 (1980).
K. Abe and C. Dawes, Archs oral. Biol.23, 367 (1978).
Author information
Authors and Affiliations
Additional information
This work is supported by a grant from the Cystic Fibrosis Research Trust, made to Dr C.J. Jones, whose help and supervision is gratefully acknowledged.
Rights and permissions
About this article
Cite this article
Wilson, S.M. An electrophoretic study of proteins secreted by the rat submandibular gland in response to autonomic agonists. Experientia 38, 608–610 (1982). https://doi.org/10.1007/BF02327077
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02327077