Summary
The ethylene glycol methacrylate gel Spheron and ion-exchangers produced by the chemical modification of this gel (the cation exchanger Spheron S and the anion exchanger Spheron DEAE) can be used for reversedphase chromatography of barbiturates and sulfonamides. In addition to the hydrophobic effect, the unique selectivities of the functional groups of Spheron materials can be utilized for the chromatographic separation of these compounds, including those difficult to resolve on octadecyl silica.
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Jandera, P., Churáček, J. & Szabó, D. Liquid chromatography on unmodified and modified Spheron gels II. Barbiturates and sulfonamides. Chromatographia 14, 7–12 (1981). https://doi.org/10.1007/BF02262055
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DOI: https://doi.org/10.1007/BF02262055