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Intranigral injected iron progressively reduces striatal dopamine metabolism

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Journal of Neural Transmission - Parkinson's Disease and Dementia Section

Summary

The striatal dopamine metabolism of the rat was followed 1, 3, and 6 weeks after unilateral intranigral iron (III) (50- and 1.5 μg) application. For both concentrations a progredient decrease of extraneuronal 3.4-dihydroxyphenylacetic acid (DOPA) levels was observed in the ipsilateral striatum.

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Wesemann, W., Blaschke, S., Solbach, M. et al. Intranigral injected iron progressively reduces striatal dopamine metabolism. J Neural Transm Gen Sect 8, 209–214 (1994). https://doi.org/10.1007/BF02260941

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  • DOI: https://doi.org/10.1007/BF02260941

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