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Membrane-active properties of crambin

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Abstract

A thionin-like protein with M. M. 5kDa has been isolated fromCrambe kotschyana seeds. It has been shown that crambin possesses, a low lytic action on erythrocytes but inhibits the Ca-ATPase of the sarcoplasmic reticulum of rabbit skeletal muscles. A disordering action of crambin on the structures of both the sarcoplasmic reticulum and liposomes has been established by ESR and microcalorimetry.

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Authors and Affiliations

  1. A. S. Sadykov Institute of Bioorganic Chemistry, Academy of Sciences of the Republic of Uzbekistan, Tashkent

    B. A. Salakhutdinov, É. T. Tadzhibaeva, M. V. Zamaraeva, I. I. Tukfatullina & T. F. Aripov

  2. Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan, Tashkent

    L. G. Mezhlum'yan, É. F. Redina & P. Kh. Yuldashev

Authors
  1. B. A. Salakhutdinov
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  2. É. T. Tadzhibaeva
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  3. M. V. Zamaraeva
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  4. I. I. Tukfatullina
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  5. T. F. Aripov
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  6. L. G. Mezhlum'yan
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  7. É. F. Redina
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  8. P. Kh. Yuldashev
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Additional information

Translated from Khimiya Prirodnykh Soedinenii, No. 1, pp. 82–88, January–February, 1998.

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Salakhutdinov, B.A., Tadzhibaeva, É.T., Zamaraeva, M.V. et al. Membrane-active properties of crambin. Chem Nat Compd 34, 62–67 (1998). https://doi.org/10.1007/BF02249689

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  • DOI: https://doi.org/10.1007/BF02249689

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