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Fluvoxamine treatment of coincident autistic disorder and obsessive-compulsive disorder: A case report

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Abstract

This is a single-case report of fluvoxamine treatment of comorbid autistic disorder (AD) and obsessive-compulsive disorder (OCD). Psychological, neuroanatomical, and neurochemical parallels are drawn between AD and OCD. The implications of this case of coincident AD and OCD, as well as the response to fluvoxamine, are discussed with respect to nosology, pathophysiology, and treatment of these disorders.

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Authors and Affiliations

  1. Department of Psychiatry, Yale University School of Medicine, USA

    Christopher J. McDougle, Lawrence H. Price & Wayne K. Goodman

  2. Clinical Neuroscience Research Unit, Ribicoff Research Facilities, Connecticut Mental Health Center, New Haven

    Christopher J. McDougle, Lawrence H. Price & Wayne K. Goodman

Authors
  1. Christopher J. McDougle
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  2. Lawrence H. Price
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  3. Wayne K. Goodman
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Additional information

This work was supported in part by grants MH-25642, MH-30929, MH-36229, and MH- 00579 from the Public Health Service, Bethesda, Maryland, and by the State of Connecticut. The authors express their thanks to Kim Sass for performing the psychological testing and to Betsy Kyle for typing the manuscript.

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McDougle, C.J., Price, L.H. & Goodman, W.K. Fluvoxamine treatment of coincident autistic disorder and obsessive-compulsive disorder: A case report. J Autism Dev Disord 20, 537–543 (1990). https://doi.org/10.1007/BF02216058

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  • DOI: https://doi.org/10.1007/BF02216058

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