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Stimulating effect of thromboxane B2 on isolated rat atria

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Summary

Thromboxane B2 enhanced the beating frequency and the contractile tension of isolated rat atria. Both effects were inhibited by propranolol, by pretreatment with 6-hydroxydopamine, or after inhibition of prostaglandins synthesis with indomethacin and acetylsalicylic acid.

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Authors and Affiliations

  1. Centro de Estudios Farmacológicos y de Principios Naturales (CEFAPRIN), Consejo Nacional de Investigaciones Científicas y Técnicas de la República Argentina (CONICET), V. de Obligado 2490, 1428, Buenos Aires, Argentina

    L. Sterin-Borda, L. Canga & A. L. Gimeno

Authors
  1. L. Sterin-Borda
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  2. L. Canga
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  3. A. L. Gimeno
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Additional information

This work has been supported by grant 6638 from CONICET (Argentina).

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Sterin-Borda, L., Canga, L. & Gimeno, A.L. Stimulating effect of thromboxane B2 on isolated rat atria. Experientia 37, 592–593 (1981). https://doi.org/10.1007/BF01990068

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  • DOI: https://doi.org/10.1007/BF01990068

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