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, Volume 1, Issue 3, pp 133–135 | Cite as

Resistance to picrotoxin poisoning induced by catatoxic steroids

  • Hans Selye
Research Reports

Abstract

In rats, severe and almost always fatal picrotoxin poisoning can be prevented by various steroids such as ethylestrenol, SC-11927, spironolactone, norbolethone, oxandrolone, prednisolone and progesterone. On the other hand, triamcinolone, desoxycorticosterone, hydroxydione, cholesterol and β-sitosterol do not prevent picrotoxin convulsions.

There appears to be a close relationship between the ability of various steroids to protect against picrotoxin convulsions and their catatoxic actions previously observed in other test systems.

Keywords

Cholesterol Steroid Progesterone Prednisolone Spironolactone 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Birkhäuser Verlag 1970

Authors and Affiliations

  • Hans Selye
    • 1
  1. 1.Institut de Médecine et de Chirurgie expérimentalesUniversité de MontréalMontréalCanada

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