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Characteristic responses to L-dopa of cerebral blood flow and EEG pattern in stroke-prone spontaneously hypertensive rats

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Summary

L-Dopa given i.p. increased regional cerebral blood flow and influenced EEG patterns in stroke-prone spontaneously hypertensive, but not in normotensive rats. The feasibility of this approach for determining the pathology of the cerebral vessels and the blood-brain barrier warrants further study.

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Authors and Affiliations

  1. Academy of Medicine, Warsaw, Poland

    Krystyna Skolasińska,  Y. Yamori, M. Kihara, Y. Nara & R. Horie

  2. Japan Stroke Prevention Center, 693, Izumo, Japan

    Krystyna Skolasińska,  Y. Yamori, M. Kihara, Y. Nara & R. Horie

  3. Dept. of Pathology, Shimane Medical University, 693, Izumo, Japan

    Krystyna Skolasińska,  Y. Yamori, M. Kihara, Y. Nara & R. Horie

Authors
  1. Krystyna Skolasińska
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  2. Y. Yamori
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  3. M. Kihara
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  4. Y. Nara
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  5. R. Horie
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Additional information

Acknowledgments. This study was supported by Science and Technology Agency of JapaneseGovernment, Japanese Ministry of Education and Ministry of Health and Welfare. We thank M. Ohara for editing the manuscript.

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Skolasińska, K., Yamori, Y., Kihara, M. et al. Characteristic responses to L-dopa of cerebral blood flow and EEG pattern in stroke-prone spontaneously hypertensive rats. Experientia 37, 997–998 (1981). https://doi.org/10.1007/BF01971801

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  • DOI: https://doi.org/10.1007/BF01971801

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