Summary
It is suggested that ouabain promotes catecholamine release by causing a rise in intracellular Na+ which, in turn, causes an elevated steady-state level of intracellular Ca2+. It is suggested that the Na+−K+-ATPase is not directly involved in exocytosis at either adrenergic or cholinergic synapses.
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Duncan, C.J. The action of ouabain in promoting the release of catecholamines. Experientia 33, 923–924 (1977). https://doi.org/10.1007/BF01951283
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DOI: https://doi.org/10.1007/BF01951283